SCHEMBL18878659

SCHEMBL18878659

O=CNCCC(=O)NCCCC(=O)O

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 1/20 0.53
EPHX2 P34913 8/20 0.49
MEN1 O00255 1/20 0.46
MAPT P10636 1/20 0.46
KMT2A Q03164 1/20 0.46
SLC6A5 Q9Y345 1/20 0.46
LMNA P02545 1/20 0.46
TSHR P16473 1/20 0.46
ATM Q13315 1/20 0.46
ADRA1A P35348 1/20 0.46
KDM4E B2RXH2 1/20 0.45
CASP2 P42575 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17347892 0.92 EPHX2 (0.53) PRMT1EPHX2MEN1MAPTKMT2A
SCHEMBL1401106 0.83
SCHEMBL23728799 0.82 EPHX2 (0.39) PRMT1EPHX2MEN1MAPTKMT2A
SCHEMBL17760454 0.81 PRMT1 (0.55) PRMT1EPHX2ADRA1AKDM4E
SCHEMBL17761130 0.81 PRMT1 (0.55) PRMT1EPHX2ADRA1AKDM4E
SCHEMBL2806091 0.81 ATM (0.57) PRMT1EPHX2MEN1MAPTKMT2A
SCHEMBL16710251 0.80 FAAH (0.43) PRMT1EPHX2MEN1MAPTKMT2A
SCHEMBL15399971 0.79 TSHR (0.65) PRMT1EPHX2MEN1MAPTKMT2A
SCHEMBL9717385 0.79 TSHR (0.59) PRMT1EPHX2MEN1MAPTKMT2A
SCHEMBL2811862 0.79 PRMT1 (0.60) PRMT1EPHX2MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170146549-A1 ISOBARIC MASS LABELS ELECTROPHORETICS LIMITED (GB) 2017-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170146549-A1 ISOBARIC MASS LABELS SRMS, PTMS, QPCTL PRMT1 88/4885EPHX2 450/4885MEN1 1576/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.