Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 9/20 | 0.96 |
| ▸ | GABRP | O00591 | 5/20 | 0.96 |
| ▸ | GABRD | O14764 | 5/20 | 0.96 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.96 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.96 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.96 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.96 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.96 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.96 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.96 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.96 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.96 |
| ▸ | GABRE | P78334 | 5/20 | 0.96 |
| ▸ | GABRA6 | Q16445 | 5/20 | 0.96 |
| ▸ | GABRG1 | Q8N1C3 | 5/20 | 0.96 |
| ▸ | GABRG3 | Q99928 | 5/20 | 0.96 |
| ▸ | GABRQ | Q9UN88 | 5/20 | 0.96 |
| ▸ | PARP1 | P09874 | 4/20 | 0.96 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.96 |
| ▸ | NPC1 | O15118 | 2/20 | 0.96 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Flavone SCHEMBL15676601 | 0.98 | TNKS (1.00) | TNKSGABRPGABRDGABRA1GABRB1 | |
| Flavone SCHEMBL31316377 | 0.98 | TNKS (1.00) | TNKSGABRPGABRDGABRA1GABRB1 | |
| Flavone SCHEMBL28248986 | 0.98 | TNKS (1.00) | TNKSGABRPGABRDGABRA1GABRB1 | |
| Flavone SCHEMBL30542161 | 0.98 | TNKS (1.00) | TNKSGABRPGABRDGABRA1GABRB1 | |
| Flavone SCHEMBL18879 | 0.98 | TNKS (1.00) | TNKSGABRPGABRDGABRA1GABRB1 | |
| Flavone SCHEMBL1660769 | 0.96 | TNKS (0.96) | TNKSGABRPGABRDGABRA1GABRB1 | |
| Flavone SCHEMBL3090011 | 0.96 | TNKS (0.96) | TNKSGABRPGABRDGABRA1GABRB1 | |
| Flavone SCHEMBL6908621 | 0.96 | TNKS (0.96) | TNKSGABRPGABRDGABRA1GABRB1 | |
| Flavone SCHEMBL31099335 | 0.96 | TNKS (0.96) | TNKSGABRPGABRDGABRA1GABRB1 | |
| Flavone SCHEMBL9530678 | 0.96 | TNKS (0.96) | TNKSGABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112056557-B | Huyou peel flavone gel ball and preparation method and application thereof | 中国农业大学 | 2022-04-15 | — | — | CN | claimed |
| CN-112056557-A | Huyou peel flavone gel ball and preparation method and application thereof | 中国农业大学 | 2020-12-11 | — | — | CN | claimed |
| CN-112056557-B | Huyou peel flavone gel ball and preparation method and application thereof | 中国农业大学 | 2022-04-15 | — | — | CN | disclosed |
| CN-112056557-B | Huyou peel flavone gel ball and preparation method and application thereof | 中国农业大学 | 2022-04-15 | — | — | CN | disclosed |
| CN-112056557-A | Huyou peel flavone gel ball and preparation method and application thereof | 中国农业大学 | 2020-12-11 | — | — | CN | disclosed |
| CN-112056557-A | Huyou peel flavone gel ball and preparation method and application thereof | 中国农业大学 | 2020-12-11 | — | — | CN | disclosed |
| EP-3193822-A2 | POLYPHENOL/FLAVONOID COMPOSITIONS AND METHODS OF FORMULATING ORAL HYGIENIC PRODUCTS | Vizuri Health Sciences LLC (US) | 2017-07-26 | — | — | EP | disclosed |
| WO-2017048617-A1 | POLYPHENOL/FLAVONOID COMPOSITIONS AND METHODS OF FORMULATING ORAL HYGIENIC PRODUCTS | VIZURI HEALTH SCIENCES LLC (US) | 2017-03-23 | — | — | WO | disclosed |
| US-20170071840-A1 | POLYPHENOL/FLAVONOID COMPOSITIONS AND METHODS OF FORMULATING ORAL HYGIENIC PRODUCTS | VIZURI HEALTH SCIENCES LLC | 2017-03-16 | — | — | US | disclosed |
| WO-2016044297-A2 | POLYPHENOL/FLAVONOID COMPOSITIONS AND METHODS OF FORMULATING ORAL HYGIENIC PRODUCTS | VIZURI HEALTH SCIENCES LLC (US) | 2016-03-24 | — | — | WO | disclosed |
| US-20160074298-A1 | POLYPHENOL/FLAVONOID COMPOSITIONS AND METHODS OF FORMULATING ORAL HYGIENIC PRODUCTS | VIZURI HEALTH SCIENCES LLC | 2016-03-17 | — | — | US | disclosed |
| WO-2014145602-A1 | POLYPHENOL/FLAVONOID COMPOSITIONS AND METHODS OF FORMULATING ORAL HYGIENIC PRODUCTS | API GENESIS LLC (US) | 2014-09-18 | — | — | WO | disclosed |
| CN-101744868-B | Application of semen astragali complanati total flavone extract in preparation of medicine for preventing and treating pulmonary fibrosis | SUZHOU RES INST OF CHINESE MEDICINE | 2012-05-02 | — | — | CN | disclosed |
| CN-101744868-A | Application of semen astragali complanati general flavone extractives in the preparation of pulmonary fibrosis prevention drugs | SUZHOU RES INST OF CHINESE MED | 2010-06-23 | — | — | CN | disclosed |
| CN-1251700-C | Application of flatstem milkvetch seed and its extract in the preparation of anti hepatic fibrosis medicine and anticancer medicine | SUZHOU INST OF CHINESE MATERIA (CN) | 2006-04-19 | — | — | CN | disclosed |
| CN-1544011-A | Application of flatstem milkvetch seed and its extract in the preparation of anti hepatic fibrosis medicine and anticancer medicine | 苏州中药研究所 | 2004-11-10 | — | — | CN | disclosed |
| CN-1468859-A | Longbract cattail general flavone extractive and its prepn and use | �Ϻ���ͨ��ѧ | 2004-01-21 | — | — | CN | disclosed |
| US-6025387-A | Gastroprotective flavone/flavanone compounds with therapeutic effect on inflammatory bowel disease | DONG A PHARMACEUTICAL CO., LTD. (KR) | 2000-02-15 | — | — | US | disclosed |
| EP-0915864-A1 | GASTROPROTECTIVE FLAVONE/FLAVANONE COMPOUNDS WITH THERAPEUTIC EFFECT ON INFLAMMATORY BOWEL DISEASE | Dong A Pharmaceutical Co. Ltd. (KR) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998004541-A1 | GASTROPROTECTIVE FLAVONE/FLAVANONE COMPOUNDS WITH THERAPEUTIC EFFECT ON INFLAMMATORY BOWEL DISEASE | DONG A PHARMACEUTICAL CO., LTD. (KR) | 1998-02-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160074298-A1 | POLYPHENOL/FLAVONOID COMPOSITIONS AND METHODS OF FORMULATING ORAL HYGIENIC PRODUCTS | LPO, LCT, MPO | TNKS 3981/4885GABRP 3542/4885GABRD 3536/4885 |
| US-20170071840-A1 | POLYPHENOL/FLAVONOID COMPOSITIONS AND METHODS OF FORMULATING ORAL HYGIENIC PRODUCTS | LPO, LCT, MPO | TNKS 3981/4885GABRP 3542/4885GABRD 3536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.