Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 4/20 | 0.32 |
| ▸ | GABRD | O14764 | 4/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.32 |
| ▸ | GABRE | P78334 | 4/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.32 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.32 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.32 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL169095 | 1.00 | SLC7A5 (0.36) | SLC7A5DPP4GABRPGABRDGABRA1 | |
| SCHEMBL23550736 | 0.78 | — | — | |
| SCHEMBL13046988 | 0.78 | — | — | |
| SCHEMBL12344720 | 0.78 | — | — | |
| SCHEMBL11460991 | 0.77 | TSHR (0.33) | — | |
| SCHEMBL20756163 | 0.75 | — | — | |
| SCHEMBL28399504 | 0.72 | — | — | |
| SCHEMBL5691403 | 0.72 | TP53 (0.33) | TP53 | |
| SCHEMBL7812200 | 0.72 | — | — | |
| SCHEMBL30636760 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230233436-A1 | COMPOSITIONS AND METHODS FOR INHIBITING HAIR GROWTH | OLSEN ELISE A (US) | 2023-07-27 | — | — | US | disclosed |
| US-20210220248-A1 | COMPOSITIONS AND METHODS FOR INHIBITING HAIR GROWTH | OLSEN, Elise | 2021-07-22 | — | — | US | disclosed |
| US-20200330479-A1 | COMPOSITIONS AND METHODS FOR TREATING HAIR LOSS USING NON-NATURALLY OCCURRING PROSTAGLANDINS | THE PROCTER & GAMBLE COMPANY | 2020-10-22 | — | — | US | disclosed |
| US-20190314259-A1 | COMPOSITIONS AND METHODS FOR INHIBITING HAIR GROWTH | DUKE UNIVERSITY | 2019-10-17 | — | — | US | disclosed |
| US-20190175475-A1 | COMPOSITIONS AND METHODS FOR TREATING HAIR LOSS USING NON-NATURALLY OCCURRING PROSTAGLANDINS | THE PROCTER & GAMBLE COMPANY | 2019-06-13 | — | — | US | disclosed |
| US-10159634-B2 | Compositions and methods for inhibiting hair growth | Olsen, Elise A. (US) | 2018-12-25 | — | — | US | disclosed |
| US-20180064622-A1 | COMPOSITIONS AND METHODS FOR INHIBITING HAIR GROWTH | DUKE UNIVERSITY | 2018-03-08 | — | — | US | disclosed |
| US-9877908-B2 | Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives | DUKE UNIVERSITY (US) | 2018-01-30 | — | — | US | disclosed |
| US-20170348214-A1 | COMPOSITIONS AND METHODS FOR TREATING HAIR LOSS USING NON-NATURALLY OCCURRING PROSTAGLANDINS | THE PROCTER & GAMBLE COMPANY | 2017-12-07 | — | — | US | disclosed |
| US-20170239160-A1 | COSMETIC AND PHARMACEUTICAL COMPOSITIONS AND METHODS USING 2-DECARBOXY-2-PHOSPHINICO DERIVATIVES | THE PROCTER & GAMBLE COMPANY | 2017-08-24 | — | — | US | disclosed |
| US-7074942-B2 | 2-decarboxy-2-phosphinico prostaglandin derivatives and methods for their preparation and use | THE PROCTER & GAMBLE COMPANY (US) | 2006-07-11 | — | — | US | disclosed |
| US-20060121069-A1 | Compositions and methods for treating hair loss using oximyl and hydroxylamino prostaglandins | DUKE UNIVERSITY (US) | 2006-06-08 | — | — | US | disclosed |
| US-20050222232-A1 | prostaglandin F analogs, such as 13,14-dihydro-15-(2-benzathiozolyl) pentanor Prostaglandin F1 alpha, with other hair growth stimulant; topically to the skin; can arrest hair loss, reverse hair loss, and promote hair growth; cosmetics | DUKE UNIVERSITY | 2005-10-06 | — | — | US | disclosed |
| US-20050124587-A1 | 2-Decarboxy-2-phosphinico prostaglandin derivatives and methods for their preparation and use | THE PROCTER & GAMBLE COMPANY | 2005-06-09 | — | — | US | disclosed |
| US-20050124588-A1 | 2-Decarboxy-2-phosphinico prostaglandin derivatives and methods for their preparation and use | THE PROCTER & GAMBLE COMAPANY | 2005-06-09 | — | — | US | disclosed |
| US-6894175-B1 | 2-Decarboxy-2-phosphinico prostaglandin derivatives and methods for their preparation and use | THE PROCTER & GAMBLE COMPANY (US) | 2005-05-17 | — | — | US | disclosed |
| US-20020172693-A1 | prostaglandin F analogs, such as 13,14-dihydro-15-(2-benzathiozolyl) pentanor Prostaglandin F1 alpha, with other hair growth stimulant; topically to the skin; can arrest hair loss, reverse hair loss, and promote hair growth; cosmetics | DUKE UNIVERSITY | 2002-11-21 | — | — | US | disclosed |
| US-20020146439-A1 | Compositions and methods for treating hair loss using oximyl and hydroxylamino prostaglandins | DUKE UNIVERSITY | 2002-10-10 | — | — | US | disclosed |
| US-20020037914-A1 | Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins | DUKE UNIVERSITY | 2002-03-28 | — | — | US | disclosed |
| US-20020013294-A1 | Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives | DUKE UNIVERSITY | 2002-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (17 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020037914-A1 | Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins | PTGES, PTGES2, PTGS2 | SLC7A5 4710/4885DPP4 4746/4885GABRP 4361/4885 |
| US-20050124588-A1 | 2-Decarboxy-2-phosphinico prostaglandin derivatives and methods for their preparation and use | PTGDR2, PTGES2, PTGS2 | SLC7A5 3198/4885DPP4 2694/4885GABRP 860/4885 |
| US-20020172693-A1 | prostaglandin F analogs, such as 13,14-dihydro-15-(2-benzathiozolyl) pentanor Prostaglandin F1 alpha, with other hair growth stimulant; topically to the skin; can arrest hair loss, reverse hair loss, and promote hair growth; cosmetics | PTGIR, PTGDR, PTGS1 | SLC7A5 4612/4885DPP4 4472/4885GABRP 1183/4885 |
| US-20190175475-A1 | COMPOSITIONS AND METHODS FOR TREATING HAIR LOSS USING NON-NATURALLY OCCURRING PROSTAGLANDINS | PTGES, PTGS1, PTGS2 | SLC7A5 4793/4885DPP4 4557/4885GABRP 3843/4885 |
| US-20180064622-A1 | COMPOSITIONS AND METHODS FOR INHIBITING HAIR GROWTH | PTGIR, MC1R, PTGFR | SLC7A5 3353/4885DPP4 4597/4885GABRP 1987/4885 |
| US-20230233436-A1 | COMPOSITIONS AND METHODS FOR INHIBITING HAIR GROWTH | PTGIR, MC1R, PTGFR | SLC7A5 3353/4885DPP4 4597/4885GABRP 1987/4885 |
| US-20050124587-A1 | 2-Decarboxy-2-phosphinico prostaglandin derivatives and methods for their preparation and use | PTGES2, PTGES, PTGS2 | SLC7A5 4311/4885DPP4 2059/4885GABRP 579/4885 |
| US-20020146439-A1 | Compositions and methods for treating hair loss using oximyl and hydroxylamino prostaglandins | PTGES, PTGS2, PTGS1 | SLC7A5 4575/4885DPP4 4760/4885GABRP 3970/4885 |
| US-20210220248-A1 | COMPOSITIONS AND METHODS FOR INHIBITING HAIR GROWTH | PTGIR, MC1R, PTGFR | SLC7A5 3353/4885DPP4 4597/4885GABRP 1987/4885 |
| US-20060121069-A1 | Compositions and methods for treating hair loss using oximyl and hydroxylamino prostaglandins | PTGES, PTGS2, PTGS1 | SLC7A5 4575/4885DPP4 4760/4885GABRP 3970/4885 |
| US-20050222232-A1 | prostaglandin F analogs, such as 13,14-dihydro-15-(2-benzathiozolyl) pentanor Prostaglandin F1 alpha, with other hair growth stimulant; topically to the skin; can arrest hair loss, reverse hair loss, and promote hair growth; cosmetics | PTGIR, PTGDR, PTGS1 | SLC7A5 4612/4885DPP4 4472/4885GABRP 1183/4885 |
| US-20170348214-A1 | COMPOSITIONS AND METHODS FOR TREATING HAIR LOSS USING NON-NATURALLY OCCURRING PROSTAGLANDINS | PTGES, PTGS1, PTGS2 | SLC7A5 4793/4885DPP4 4557/4885GABRP 3843/4885 |
| US-20170239160-A1 | COSMETIC AND PHARMACEUTICAL COMPOSITIONS AND METHODS USING 2-DECARBOXY-2-PHOSPHINICO DERIVATIVES | BMP2, PLOD2, PTGDR2 | SLC7A5 3795/4885DPP4 2431/4885GABRP 2943/4885 |
| US-20200330479-A1 | COMPOSITIONS AND METHODS FOR TREATING HAIR LOSS USING NON-NATURALLY OCCURRING PROSTAGLANDINS | PTGES, PTGS1, PTGS2 | SLC7A5 4793/4885DPP4 4557/4885GABRP 3843/4885 |
| US-20020013294-A1 | Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives | BMP2, PLOD2, PTGDR2 | SLC7A5 3795/4885DPP4 2431/4885GABRP 2943/4885 |
| US-20190314259-A1 | COMPOSITIONS AND METHODS FOR INHIBITING HAIR GROWTH | PTGIR, MC1R, PTGFR | SLC7A5 3353/4885DPP4 4597/4885GABRP 1987/4885 |
| US-10159634-B2 | Compositions and methods for inhibiting hair growth | PTGIR, MC1R, PTGFR | SLC7A5 3353/4885DPP4 4597/4885GABRP 1987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.