SCHEMBL18889273

SCHEMBL18889273

Fc1ccc(-c2cccc3sc(CCl)cc23)cc1

nearest known ligand 0.49

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 5/20 0.49
RIPK1 Q13546 6/20 0.48
S1PR5 Q9H228 7/20 0.40
S1PR4 O95977 6/20 0.40
FFAR4 Q5NUL3 1/20 0.39
F9 P00740 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18932596 0.77 SLC9A1 (0.43) SLC9A1RIPK1S1PR5S1PR4FFAR4
SCHEMBL18889292 0.76 RIPK1 (0.60) SLC9A1RIPK1S1PR5S1PR4FFAR4
SCHEMBL9209273 0.72 HDAC3 (0.47) SLC9A1
Hydrochloric Acid SCHEMBL18889264 0.72 RIPK1 (0.53) SLC9A1RIPK1FFAR4F9
SCHEMBL18889267 0.72 SLC9A1 (0.68) SLC9A1RIPK1F9
SCHEMBL28115367 0.70 PLAU (0.47) SLC9A1
SCHEMBL829128 0.68 SLC9A1 (0.62) SLC9A1RIPK1
SCHEMBL28280395 0.66 HSD17B1 (0.44)
SCHEMBL825969 0.66 SLC9A1 (1.00) SLC9A1
SCHEMBL3470157 0.65 GFER (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3176163-B1 NOVEL INDENE DERIVATIVE, PREPARATION METHOD FOR SAME, AND PHARMACEUTICAL COMPOSITION, FOR PREVENTING OR TREATING RETINAL DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT IAC IN NAT UNIV CHUNGNAM (KR) 2019-04-17 EP disclosed
EP-3176163-A1 NOVEL INDENE DERIVATIVE, PREPARATION METHOD FOR SAME, AND PHARMACEUTICAL COMPOSITION, FOR PREVENTING OR TREATING RETINAL DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT The Industry & Academic Cooperation in Chungnam National University (IAC) (KR) 2017-06-07 EP disclosed
US-20170152268-A1 NOVEL INDENE DERIVATIVE, PREPARATION METHOD FOR SAME, AND PHARMACEUTICAL COMPOSITION, FOR PREVENTING OR TREATING RETINAL DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT MOTHER'S PHARMACEUTICAL CO., LTD. (KR) 2017-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170152268-A1 NOVEL INDENE DERIVATIVE, PREPARATION METHOD FOR SAME, AND PHARMACEUTICAL COMPOSITION, FOR PREVENTING OR TREATING RETINAL DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT RIPK1, RIPK2, RIPK3 SLC9A1 2031/4885RIPK1 1/4885S1PR5 4409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.