Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.55 |
| ▸ | CTSS | P25774 | 3/20 | 0.53 |
| ▸ | CTSK | P43235 | 2/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 5/20 | 0.49 |
| ▸ | PPARG | P37231 | 4/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1888965 | 1.00 | ACE (0.59) | ACEPTPN1CTSSCTSKCTSL | |
| SCHEMBL3470656 | 0.90 | PTPN1 (0.47) | ACEPTPN1CTSSCTSKCTSL | |
| SCHEMBL1889046 | 0.89 | CTSS (0.55) | ACEPTPN1CTSSCTSKCTSL | |
| SCHEMBL27909397 | 0.84 | ACE (0.79) | ACEPTPN1CTSSCTSKCTSL | |
| SCHEMBL21473784 | 0.84 | ACE (0.79) | ACEPTPN1CTSSCTSKCTSL | |
| SCHEMBL795685 | 0.84 | ACE (0.79) | ACEPTPN1CTSSCTSKCTSL | |
| SCHEMBL66220 | 0.84 | ACE (0.79) | ACEPTPN1CTSSCTSKCTSL | |
| SCHEMBL67020 | 0.84 | ACE (0.79) | ACEPTPN1CTSSCTSKCTSL | |
| SCHEMBL606309 | 0.84 | ACE (0.79) | ACEPTPN1CTSSCTSKCTSL | |
| Water SCHEMBL15362013 | 0.83 | ACE (0.77) | ACEPTPN1CTSSCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011061675-A1 | PROCESS FOR ENANTIOSELECTIVE PREPARATION OF NITROKETONE, AN INTERMEDIATE OF PROTEASE INHIBITORS | PIRAMAL HEALTHCARE LIMITED (IN) | 2011-05-26 | — | — | WO | disclosed |
| EP-0769003-B1 | AMINO ACID-DERIVED DIAMINOPROPANOLS | PHARMECO LAB INC (US) | 2001-05-16 | — | — | EP | disclosed |
| EP-1059285-A2 | Process for the preparation of 1,3-diamino-2-propanol and 1,3-diamino-2-propanone derivatives | Pharm-Eco Laboratories, Inc. (US) | 2000-12-13 | — | — | EP | disclosed |
| US-6063963-A | Amino acid-derived diaminopropanols | PHARM-ECO LABORATORIES, INC. (US) | 2000-05-16 | — | — | US | disclosed |
| US-5631405-A | Method of forming amino acid-derived diaminopropanols useful as chemical intermediates for protease-inhibitors | PHARM-ECO LABORATORIES, INCORPORATED (US) | 1997-05-20 | — | — | US | disclosed |
| EP-0769003-A1 | AMINO ACID-DERIVED DIAMINOPROPANOLS | Pharmeco Laboratories, Inc. (US) | 1997-04-23 | — | — | EP | disclosed |
| US-5618966-A | Method forming protease inhibitor synthetic intermediates | PHARM-ECO LABORATORIES, INCORPORATED (US) | 1997-04-08 | — | — | US | disclosed |
| US-5599994-A | Amino acid-derived diaminopropanols | PHARM-ECO LABORATORIES, INC. (US) | 1997-02-04 | — | — | US | disclosed |
| WO-1996001788-A2 | AMINO ACID-DERIVED DIAMINOPROPANOLS | PHARM-ECO LABORATORIES, INCORPORATED (US) | 1996-01-25 | — | — | WO | disclosed |
| US-5475138-A | Method preparing amino acid-derived diaminopropanols | PHARM-ECO LABORATORIES INCORPORATED (US) | 1995-12-12 | — | — | US | disclosed |