Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1888967 | 0.90 | ACE (0.59) | PTPN1ACEMAPTPOLBTDP1 | |
| SCHEMBL1888965 | 0.90 | ACE (0.59) | PTPN1ACEMAPTPOLBTDP1 | |
| SCHEMBL1691095 | 0.84 | ACE (0.60) | PTPN1ACECTSSCTSLCTSB | |
| SCHEMBL2721558 | 0.84 | ACE (0.60) | PTPN1ACECTSSCTSLCTSB | |
| SCHEMBL1889046 | 0.81 | CTSS (0.55) | PTPN1ACEMAPTPOLBTDP1 | |
| SCHEMBL3470654 | 0.76 | MAPT (0.38) | MAPTPOLBTDP1KMT2A | |
| Bicarbonate SCHEMBL3813183 | 0.75 | CTSS (0.58) | PTPN1ACECTSSCTSLCTSB | |
| SCHEMBL7554167 | 0.74 | CTSS (0.67) | ACECTSSCTSLCTSBCTSK | |
| SCHEMBL21164375 | 0.74 | CTSS (0.53) | ACEMAPTPOLBTDP1CTSS | |
| SCHEMBL29129568 | 0.73 | CTSK (0.58) | ACECTSSCTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010143150-A2 | PROCESS FOR STEREOSELECTIVE PREPARATION OF AN INTERMEDIATE OF PROTEASE INHIBITORS | PIRAMAL HEALTHCARE LIMITED (IN) | 2010-12-16 | — | — | WO | disclosed |