Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19380787 | 0.90 | GBA1 (0.74) | GBA1ALDH1A1KDM4EHTTLMNA | |
| SCHEMBL19710807 | 0.87 | BCHE (0.56) | GBA1ALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL8212538 | 0.87 | BCHE (0.56) | GBA1ALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL10500821 | 0.83 | ACHE (0.58) | GBA1ALDH1A1KDM4EHTTMAPT | |
| SCHEMBL15800410 | 0.81 | S1PR1 (0.62) | GBA1ALDH1A1KDM4EHTTFAAH | |
| SCHEMBL5512520 | 0.80 | GBA1 (0.55) | GBA1ALDH1A1KDM4EHTTLMNA | |
| SCHEMBL12197 | 0.80 | GBA1 (0.55) | GBA1ALDH1A1KDM4EHTTLMNA | |
| SCHEMBL11002867 | 0.80 | ALDH1A1 (0.55) | GBA1ALDH1A1KDM4EHTTLMNA | |
| SCHEMBL2716001 | 0.79 | GBA1 (1.00) | GBA1 | |
| SCHEMBL2918653 | 0.79 | SIGMAR1 (0.63) | ALDH1A1KDM4EFAAHMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928884-B1 | NOVEL BENZIMIDAZOLE DERIVATIVES AS EP4 ANTAGONISTS | Bayer Pharma AG (DE) | 2017-05-24 | — | — | EP | disclosed |