Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.92 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| M-Xylene SCHEMBL27645721 | 1.00 | — | — | |
| M-Xylene SCHEMBL6397624 | 0.96 | — | — | |
| M-Xylene SCHEMBL28189 | 0.96 | — | — | |
| M-Xylene SCHEMBL891494 | 0.96 | ACHE (1.00) | ACHEALDH1A1MAPK1TSHRTDP1 | |
| M-Xylene SCHEMBL28287184 | 0.93 | ACHE (0.80) | ACHEALDH1A1MAPK1TSHRTDP1 | |
| M-Xylene SCHEMBL4596533 | 0.92 | ACHE (0.92) | ACHEALDH1A1MAPK1TSHRTDP1 | |
| M-Xylene SCHEMBL2292576 | 0.92 | ACHE (0.92) | ACHEALDH1A1MAPK1TSHRTDP1 | |
| M-Xylene SCHEMBL6772614 | 0.92 | — | — | |
| M-Xylene SCHEMBL78260 | 0.92 | ACHE (0.92) | ACHEALDH1A1MAPK1TSHRTDP1 | |
| M-Xylene SCHEMBL18045662 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3383421-B1 | STAPLED HELICAL PEPTIDES AND METHODS OF SYNTHESIS | UNIV HONG KONG (CN) | 2021-05-19 | — | — | EP | disclosed |
| US-10954287-B2 | Ras binding peptides and methods of use | RA PHARMACEUTICALS, INC. (US) | 2021-03-23 | — | — | US | disclosed |
| US-20190119358-A1 | RAS BINDING PEPTIDES AND METHODS OF USE | RA PHARMACEUTICALS, INC. | 2019-04-25 | — | — | US | disclosed |
| EP-3442991-A1 | RAS BINDING PEPTIDES AND METHODS OF USE | RA Pharmaceuticals, Inc. (US) | 2019-02-20 | — | — | EP | disclosed |
| CN-109069581-A | lock ring helical peptide and synthetic method | 香港大学 | 2018-12-21 | — | — | CN | disclosed |
| EP-3383421-A1 | STAPLED HELICAL PEPTIDES AND METHODS OF SYNTHESIS | The University of Hong Kong (CN) | 2018-10-10 | — | — | EP | disclosed |
| US-10011631-B2 | Stapled helical peptides and methods of synthesis | THE UNIVERSITY OF HONG KONG (HK) | 2018-07-03 | — | — | US | disclosed |
| WO-2017181061-A1 | RAS BINDING PEPTIDES AND METHODS OF USE | RA PHARMACEUTICALS, INC. (US) | 2017-10-19 | — | — | WO | disclosed |
| WO-2017092691-A1 | STAPLED HELICAL PEPTIDES AND METHODS OF SYNTHESIS | THE UNIVERSITY OF HONG KONG (CN) | 2017-06-08 | — | — | WO | disclosed |
| US-20170152286-A1 | STAPLED HELICAL PEPTIDES AND METHODS OF SYNTHESIS | THE UNIVERSITY OF HONG KONG (HK) | 2017-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10011631-B2 | Stapled helical peptides and methods of synthesis | SPPL2B, SUCLA2, PRAP1 | ACHE 4823/4885ALDH1A1 2914/4885MAPK1 2897/4885 |
| US-10954287-B2 | Ras binding peptides and methods of use | KRAS, RASGRP1, NRAS | ACHE 4743/4885ALDH1A1 4777/4885MAPK1 248/4885 |
| US-20170152286-A1 | STAPLED HELICAL PEPTIDES AND METHODS OF SYNTHESIS | SPPL2B, SUCLA2, PRAP1 | ACHE 4823/4885ALDH1A1 2914/4885MAPK1 2897/4885 |
| US-20190119358-A1 | RAS BINDING PEPTIDES AND METHODS OF USE | KRAS, RASGRP1, NRAS | ACHE 4743/4885ALDH1A1 4777/4885MAPK1 248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.