Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10041689 | 0.70 | MAPT (0.41) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL10041690 | 0.68 | KDM4E (0.54) | LMNAPKMMEN1KMT2AALDH1A1 | |
| SCHEMBL14644256 | 0.66 | NPC1 (0.57) | PKMMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL14644096 | 0.66 | NPC1 (0.61) | LMNAPKMMEN1KMT2AALDH1A1 | |
| SCHEMBL14644197 | 0.65 | LMNA (0.50) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL10564897 | 0.64 | KMT2A (0.46) | KMT2AALDH1A1KDM4EGLAGAA | |
| SCHEMBL29364307 | 0.64 | TP53 (0.61) | LMNAALDH1A1MAPTTDP1RXFP1 | |
| SCHEMBL440944 | 0.64 | TP53 (0.61) | LMNAALDH1A1MAPTTDP1RXFP1 | |
| SCHEMBL381603 | 0.62 | PTPN1 (0.56) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL29416774 | 0.62 | PTPN1 (0.56) | LMNAMEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2311826-B1 | NOVEL NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | LG CHEMICAL LTD (KR) | 2017-05-24 | — | — | EP | disclosed |