Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | F11 | P03951 | 1/20 | 0.31 |
| ▸ | F7 | P08709 | 1/20 | 0.31 |
| ▸ | F3 | P13726 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18892498 | 1.00 | LMNA (0.33) | LMNACYSLTR2CYSLTR1RAB9AMAPT | |
| SCHEMBL18892524 | 0.86 | HDAC1 (0.37) | LMNARAB9AMAPTMEN1KMT2A | |
| SCHEMBL18892428 | 0.85 | RAB9A (0.38) | LMNACYSLTR2CYSLTR1RAB9AMAPT | |
| SCHEMBL17705271 | 0.81 | LRRK2 (0.41) | LMNARAB9ATP53L3MBTL1P2RX4 | |
| SCHEMBL17705256 | 0.81 | LRRK2 (0.41) | LMNARAB9ATP53L3MBTL1P2RX4 | |
| SCHEMBL18892525 | 0.77 | LMNA (0.47) | LMNAMAPTMEN1KMT2AKDM4E | |
| SCHEMBL18892502 | 0.76 | LMNA (0.36) | LMNARAB9AMAPTMEN1KMT2A | |
| SCHEMBL16293780 | 0.76 | LRRK2 (0.35) | LMNATP53L3MBTL1P2RX4 | |
| SCHEMBL16294815 | 0.76 | LRRK2 (0.35) | LMNATP53L3MBTL1P2RX4 | |
| SCHEMBL18892497 | 0.76 | LMNA (0.45) | LMNAMAPTMEN1KMT2AAPOBEC3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9657006-B2 | Macrocyclic factor VIIa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-05-23 | — | — | US | disclosed |