Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
| ▸ | CPN1 | P15169 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10266053 | 0.75 | CYP1A2 (0.38) | HTR1AGNAI3GNAO1GNAI1CACNA2D1 | |
| SCHEMBL12103403 | 0.74 | CACNA2D1 (0.40) | HTR1AGNAI3GNAO1GNAI1CACNA2D1 | |
| SCHEMBL31467987 | 0.74 | NCF1 (0.38) | HTR1AGNAI3GNAO1GNAI1CACNA2D1 | |
| SCHEMBL18780643 | 0.74 | GNAO1 (0.34) | GNAI3GNAO1GNAI1NCF1CPN1 | |
| SCHEMBL12617369 | 0.74 | CACNA2D1 (0.40) | HTR1AGNAI3GNAO1GNAI1CACNA2D1 | |
| SCHEMBL8967209 | 0.72 | NCF1 (0.38) | HTR1AGNAI3GNAO1GNAI1CACNA2D1 | |
| SCHEMBL13600026 | 0.72 | NCF1 (0.41) | HTR1AGNAI3GNAO1GNAI1NCF1 | |
| SCHEMBL19534541 | 0.72 | NCF1 (0.41) | HTR1AGNAI3GNAO1GNAI1NCF1 | |
| SCHEMBL13600070 | 0.71 | CYP1A2 (0.35) | HTR1AGNAI3GNAO1GNAI1CACNA2D1 | |
| SCHEMBL13998211 | 0.69 | CYP1A2 (0.37) | GNAI3GNAO1GNAI1CYP1A2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9657079-B2 | Truncated GLP-1 derivatives and their therapeutical use | NOVO NORDISK A/S (DK) | 2017-05-23 | — | — | US | disclosed |