SCHEMBL12103403

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12617369	1.00	CACNA2D1 (0.40)	CACNA2D1CACNA1BCACNB1CACNA1CREN
	SCHEMBL31467987	0.85	NCF1 (0.38)	CACNA2D1CACNA1BCACNB1CACNA1CHTR1A
	SCHEMBL5967438	0.83	—	—
	SCHEMBL1295911	0.83	CPN1 (0.41)	RENACEALDH1A1CPN1CPB2
	SCHEMBL11310195	0.81	CPN1 (0.44)	RENACEMAPTCPN1CPB2
	SCHEMBL6559712	0.78	ALDH1A1 (0.37)	CACNA2D1CACNA1CRENACEALDH1A1
	SCHEMBL1208925	0.78	ALDH1A1 (0.55)	RENACEALDH1A1
	SCHEMBL8651989	0.78	ALDH1A1 (0.55)	RENACEALDH1A1
	SCHEMBL6808670	0.78	ALDH1A1 (0.55)	RENACEALDH1A1
	SCHEMBL8967209	0.75	NCF1 (0.38)	CACNA2D1CACNA1BCACNB1CACNA1CHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.