Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.52 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.51 |
| ▸ | DHFR | P00374 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SORD | Q00796 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL136881 | 0.85 | PLD1 (0.56) | KDM4EALDH1A1MAPTHSD17B10PLD1 | |
| SCHEMBL13168323 | 0.82 | HSD17B10 (0.53) | KDM4EALDH1A1MAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL15800694 | 0.80 | PLD1 (0.73) | KDM4EALDH1A1MAPTHSD17B10PLD1 | |
| SCHEMBL21353591 | 0.80 | — | — | |
| SCHEMBL29857922 | 0.80 | PLD1 (0.73) | KDM4EALDH1A1MAPTHSD17B10PLD1 | |
| SCHEMBL19440754 | 0.80 | LMNA (0.47) | KDM4EALDH1A1MAPTHSD17B10HRH3 | |
| SCHEMBL16587650 | 0.79 | KDM4E (0.50) | KDM4EALDH1A1MAPTHSD17B10PLD1 | |
| SCHEMBL4563402 | 0.78 | HTT (0.56) | KDM4EALDH1A1MAPTPLD1SMN1; SMN2 | |
| SCHEMBL3867807 | 0.78 | KDM4E (0.64) | KDM4EALDH1A1MAPTHSD17B10HRH3 | |
| SCHEMBL9639408 | 0.77 | KDM4E (0.59) | KDM4EALDH1A1MAPTHSD17B10PLD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9656956-B2 | Benzene, pyridine, and pyridazine derivatives | ESANEX, INC. (US) | 2017-05-23 | — | — | US | disclosed |