Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.48 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | ESR1 | P03372 | 3/20 | 0.48 |
| ▸ | SHBG | P04278 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.48 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.48 |
| ▸ | STS | P08842 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13804515 | 1.00 | HSD17B10 (0.50) | HSD17B10AKR1C3TSHRMAPK1CYP19A1 | |
| SCHEMBL9830530 | 0.88 | HSD17B10 (0.51) | HSD17B10AKR1C3TSHRMAPK1CYP19A1 | |
| SCHEMBL5679460 | 0.84 | AKR1C3 (0.58) | HSD17B10AKR1C3TSHRMAPK1CYP19A1 | |
| SCHEMBL6853827 | 0.82 | ESR1 (0.49) | HSD17B10AKR1C3TSHRMAPK1CYP19A1 | |
| SCHEMBL13804527 | 0.81 | HSD17B10 (0.69) | HSD17B10AKR1C3TSHRMAPK1CYP19A1 | |
| SCHEMBL4183897 | 0.81 | HSD17B10 (0.69) | HSD17B10AKR1C3TSHRMAPK1CYP19A1 | |
| SCHEMBL9972605 | 0.81 | ESR1 (0.50) | HSD17B10AKR1C3TSHRMAPK1CYP19A1 | |
| SCHEMBL13807784 | 0.81 | ESR1 (0.50) | HSD17B10AKR1C3TSHRMAPK1CYP19A1 | |
| SCHEMBL3864635 | 0.81 | ESR1 (0.50) | HSD17B10AKR1C3TSHRMAPK1CYP19A1 | |
| SCHEMBL6849270 | 0.81 | ESR1 (0.50) | HSD17B10AKR1C3TSHRMAPK1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070298456-A1 | Microbiological process for the production of 7-substitued 11-hydroxy steroids, 7,17-substituted 11-halogen steroids, and uses thereof | ZORN LUDWIG | 2007-12-27 | — | — | US | claimed |
| US-20050090477-A1 | Microbiological process for the production of 7-substituted 11-hydroxy steroids, 7,17-substituted 11-halogen steroids that can be produced therefrom, their process for production and use as well as pharmaceutical prepartions that contain these compounds, as well as 7-substituted estra-1,3,5(10)-trienses that can be produced therefrom | SCHERING AG (DE) | 2005-04-28 | — | — | US | claimed |
| EP-1947107-B1 | PROCESS FOR PRODUCTION OF STEROID COMPOUND | STANFORD RES INST INT (US) | 2012-10-17 | — | — | EP | disclosed |
| US-7935838-B2 | Process for production of steroid compound | SRI INTERNATIONAL (US) | 2011-05-03 | — | — | US | disclosed |
| US-20090253922-A1 | Process for Production of Steroid Compound | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2009-10-08 | — | — | US | disclosed |
| EP-1947107-A1 | PROCESS FOR PRODUCTION OF STEROID COMPOUND | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2008-07-23 | — | — | EP | disclosed |
| US-20070298456-A1 | Microbiological process for the production of 7-substitued 11-hydroxy steroids, 7,17-substituted 11-halogen steroids, and uses thereof | ZORN LUDWIG | 2007-12-27 | — | — | US | disclosed |
| US-7262023-B2 | Microbiological process for the production of 7-substituted 11-hydroxy steroids, 7,17-substituted 11-Halogen steroids and uses thereof | BAYER SCHERING PHARMA AG (DE) | 2007-08-28 | — | — | US | disclosed |
| US-20060270845-A1 | 16-Hydroxyestratrienes as selectively active estrogens | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2006-11-30 | — | — | US | disclosed |
| US-7109360-B1 | 16-hydroxyestratrienes as selectively active estrogens | SCHERING AG (DE) | 2006-09-19 | — | — | US | disclosed |
| EP-1144431-B1 | 16-HYDROXYESTRATRIENES AS SELECTIVE ESTROGENS | SCHERING AG (DE) | 2005-12-21 | — | — | EP | disclosed |
| EP-1580192-A2 | 16-Hydroxyestratrienes as selective estrogens | Schering AG (DE) | 2005-09-28 | — | — | EP | disclosed |
| US-20050090477-A1 | Microbiological process for the production of 7-substituted 11-hydroxy steroids, 7,17-substituted 11-halogen steroids that can be produced therefrom, their process for production and use as well as pharmaceutical prepartions that contain these compounds, as well as 7-substituted estra-1,3,5(10)-trienses that can be produced therefrom | SCHERING AG (DE) | 2005-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060270845-A1 | 16-Hydroxyestratrienes as selectively active estrogens | ESR1, ESR2, ESRRA | HSD17B10 140/4885AKR1C3 464/4885TSHR 1039/4885 |
| US-20090253922-A1 | Process for Production of Steroid Compound | CYP11B2, CYP11B1, CYP21A2 | HSD17B10 57/4885AKR1C3 61/4885TSHR 931/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.