Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 8/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12936669 | 0.88 | CCR1 (0.49) | CCR1CHRM2CCR5 | |
| SCHEMBL18895978 | 0.88 | CCR1 (0.47) | CCR1CHRM2CCR5 | |
| SCHEMBL15478403 | 0.79 | DRD2 (0.36) | CCR1 | |
| SCHEMBL15478333 | 0.79 | DRD2 (0.40) | CCR1 | |
| SCHEMBL15478335 | 0.78 | DRD2 (0.34) | CCR1 | |
| SCHEMBL10288021 | 0.78 | CCR1 (0.75) | CCR1CHRM2CCR5 | |
| SCHEMBL15478355 | 0.77 | CCR1 (0.38) | CCR1 | |
| SCHEMBL15478375 | 0.77 | CCR1 (0.50) | CCR1CHRM2 | |
| SCHEMBL15478359 | 0.77 | CCR1 (0.38) | CCR1 | |
| SCHEMBL15478402 | 0.74 | DRD2 (0.34) | CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663537-B2 | Chemokine receptor antagonists and methods of use | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2017-05-30 | — | — | US | disclosed |