SCHEMBL1889605

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12673194	0.91	NPC1 (0.44)	LMNAKDM4ENPC1ALDH1A1RAB9A
	SCHEMBL12673136	0.89	LMNA (0.52)	LMNAKDM4ENPC1ALDH1A1RAB9A
	SCHEMBL12673090	0.85	LMNA (0.51)	LMNAKDM4ENPC1ALDH1A1RAB9A
	SCHEMBL12673187	0.85	LMNA (0.48)	LMNAKDM4ENPC1ALDH1A1RAB9A
	SCHEMBL12673101	0.83	PARP1 (0.47)	LMNAKDM4ENPC1ALDH1A1RAB9A
	SCHEMBL17787662	0.83	ALDH1A1 (0.43)	ALDH1A1RAB9AMAPK1MEN1KMT2A
	SCHEMBL12673371	0.83	LMNA (0.51)	LMNAKDM4ENPC1ALDH1A1RAB9A
	SCHEMBL12673138	0.82	LMNA (0.55)	LMNAKDM4ENPC1ALDH1A1RAB9A
	SCHEMBL1898119	0.82	LMNA (0.53)	LMNAKDM4ENPC1ALDH1A1RAB9A
	SCHEMBL1891554	0.82	LMNA (0.47)	LMNAKDM4ENPC1ALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.