Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALPL | P05186 | 1/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.53 |
| ▸ | ALPG | P10696 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | PLEC | Q15149 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 15/20 | 0.50 |
| ▸ | CA1 | P00915 | 13/20 | 0.50 |
| ▸ | CA2 | P00918 | 13/20 | 0.50 |
| ▸ | CA12 | O43570 | 5/20 | 0.48 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1103795 | 0.85 | USP2 (0.69) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL22651493 | 0.80 | USP2 (0.68) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL16283416 | 0.79 | USP2 (0.67) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL1437042 | 0.78 | USP2 (0.78) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL20254033 | 0.78 | USP2 (0.77) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL24300550 | 0.78 | USP2 (0.59) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL10098714 | 0.77 | USP2 (0.76) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL3481432 | 0.77 | USP2 (1.00) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL30023431 | 0.77 | USP2 (1.00) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL18239274 | 0.77 | USP2 (0.76) | USP2L3MBTL1MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663454-B2 | 3-aryl propiolonitrile compounds for thiol labeling | UNIVERSITE DE STRASBOURG (FR) | 2017-05-30 | — | — | US | disclosed |