Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 7/20 | 0.35 |
| ▸ | GRM5 | P41594 | 6/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | CDK7 | P50613 | 1/20 | 0.34 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.34 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13334980 | 0.79 | CCR2 (0.54) | CCR2 | |
| SCHEMBL4152429 | 0.77 | GRM1 (0.54) | SYKWNT3AGRM1GRM5SCN9A | |
| SCHEMBL13627676 | 0.72 | CDK9 (0.37) | SYKTRPV1WNT3AGRM1GRM5 | |
| SCHEMBL13741759 | 0.72 | CCR2 (0.52) | CCR2 | |
| SCHEMBL3322631 | 0.72 | CCR2 (0.52) | CCR2 | |
| SCHEMBL18901551 | 0.72 | SYK (0.46) | SYKTRPV1WNT3AGRM1GRM5 | |
| SCHEMBL3327341 | 0.71 | CCR2 (0.57) | CCR2 | |
| SCHEMBL4137979 | 0.71 | CCR2 (0.49) | CCR2 | |
| SCHEMBL3021208 | 0.71 | CCR2 (0.54) | CCR2 | |
| SCHEMBL3326632 | 0.71 | TRPV1 (0.43) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763351-B9 | 3-AMINOCYCLOPENTANECARBOXAMIDES AS MODULATORS OF CHEMOKINE RECEPTORS | INCYTE HOLDINGS CORP (US) | 2017-05-31 | — | — | EP | disclosed |