Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 5/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 7/20 | 0.35 |
| ▸ | GRM5 | P41594 | 6/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13627659 | 0.84 | CYP11B2 (0.38) | TRPV1SCN9A | |
| SCHEMBL13627657 | 0.83 | TRPV1 (0.38) | TRPV1 | |
| SCHEMBL13628370 | 0.81 | NPC1 (0.44) | SYK | |
| SCHEMBL13627655 | 0.81 | PDK4 (0.42) | SCN9AGRM1GRM5SYK | |
| SCHEMBL13627656 | 0.79 | CCR2 (0.44) | — | |
| SCHEMBL4152429 | 0.77 | GRM1 (0.54) | CDK9CCNT1SCN9AWNT3AGRM1 | |
| SCHEMBL18901554 | 0.72 | CCR2 (0.39) | TRPV1SCN9AWNT3AGRM1GRM5 | |
| SCHEMBL18901551 | 0.72 | SYK (0.46) | CDK9CCNT1TRPV1SCN9AWNT3A | |
| SCHEMBL13334980 | 0.72 | CCR2 (0.54) | — | |
| SCHEMBL3326632 | 0.71 | TRPV1 (0.43) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7618970-B2 | 3-aminocyclopentanecarboxamides as modulators of chemokine receptors | INCYTE CORPORATION (US) | 2009-11-17 | — | — | US | disclosed |