Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23152943 | 0.75 | EPHX1 (0.37) | EPHX1ALDH1A1HSD17B10MGAMGAA | |
| SCHEMBL13164954 | 0.74 | ALDH1A1 (0.55) | EPHX1ALDH1A1LMNAHSD17B10MGAM | |
| SCHEMBL20388578 | 0.71 | PKM (0.40) | ALDH1A1HRH3KDM4EPKM | |
| SCHEMBL6240076 | 0.70 | TDP1 (0.42) | EPHX1HRH3KDM4E | |
| SCHEMBL14733164 | 0.70 | TDP1 (0.42) | EPHX1HRH3KDM4E | |
| SCHEMBL6240167 | 0.70 | TDP1 (0.42) | EPHX1HRH3KDM4E | |
| SCHEMBL29323361 | 0.70 | KDM4E (0.47) | ALDH1A1HRH3KDM4EPKMLMNA | |
| SCHEMBL8076234 | 0.69 | MCL1 (0.47) | ALDH1A1HRH3KDM4EHSD17B10GAA | |
| SCHEMBL752505 | 0.69 | NAALAD2 (0.46) | EPHX1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL20707104 | 0.68 | EPHX1 (0.33) | EPHX1ALDH1A1PKMLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2328865-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-05-31 | — | — | EP | disclosed |