Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28168389 | 0.85 | NAALAD2 (0.43) | NAALAD2ALDH1A1KDM4CTDP1CTSS | |
| SCHEMBL748437 | 0.83 | TSHR (0.44) | NAALAD2ALDH1A1KDM4CEPHX1TSHR | |
| SCHEMBL3400195 | 0.80 | EPHX1 (0.43) | NAALAD2ALDH1A1EPHX1 | |
| SCHEMBL28641121 | 0.78 | NAALAD2 (0.47) | NAALAD2ALDH1A1KDM4CLMNAHSD17B10 | |
| SCHEMBL13164954 | 0.77 | ALDH1A1 (0.55) | ALDH1A1KDM4CEPHX1LMNAHSD17B10 | |
| SCHEMBL24633806 | 0.74 | NAALAD2 (0.44) | NAALAD2ALDH1A1KDM4CEPHX1TDP1 | |
| SCHEMBL192125 | 0.74 | ALDH1A1 (0.35) | ALDH1A1KDM4CEPHX1TDP1 | |
| SCHEMBL27966323 | 0.74 | EPHX1 (0.33) | ALDH1A1KDM4CEPHX1 | |
| SCHEMBL27028681 | 0.74 | NAALAD2 (0.44) | NAALAD2ALDH1A1KDM4CEPHX1HSD17B10 | |
| SCHEMBL24633751 | 0.74 | NAALAD2 (0.44) | NAALAD2ALDH1A1KDM4CEPHX1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430014-A1 | ANTIVIRAL COMPOUNDS | Gilead Sciences, Inc. (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010132601-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-11-18 | — | — | WO | disclosed |