Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP7 | P09237 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15368155 | 1.00 | CA12 (0.36) | CA12CA14TP53SMN1; SMN2LMNA | |
| SCHEMBL15368180 | 0.80 | CA12 (0.38) | CA12CA14SMN1; SMN2LMNAGAA | |
| SCHEMBL15898485 | 0.79 | CA12 (0.34) | CA12CA14SMN1; SMN2 | |
| SCHEMBL21688210 | 0.78 | CTSS (0.34) | TP53SMN1; SMN2LMNAGAAHPGD | |
| SCHEMBL23986916 | 0.78 | CTSS (0.34) | TP53SMN1; SMN2LMNAGAAHPGD | |
| SCHEMBL22697281 | 0.77 | TP53 (0.43) | TP53SMN1; SMN2LMNAGAAHPGD | |
| SCHEMBL19191380 | 0.75 | CA12 (0.35) | CA12CA14SMN1; SMN2 | |
| SCHEMBL2551696 | 0.74 | ALDH1A1 (0.44) | TP53SMN1; SMN2LMNAGAAHPGD | |
| SCHEMBL73645 | 0.74 | ALDH1A1 (0.44) | TP53SMN1; SMN2LMNAGAAHPGD | |
| SCHEMBL16750043 | 0.74 | ALDH1A1 (0.44) | TP53SMN1; SMN2LMNAGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601188-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-10-18 | — | — | EP | disclosed |
| EP-2328865-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-05-31 | — | — | EP | disclosed |