Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP3 | P08254 | 2/20 | 0.35 |
| ▸ | MMP13 | P45452 | 2/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16750043 | 1.00 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2LMNAGAAHPGD | |
| SCHEMBL73645 | 1.00 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2LMNAGAAHPGD | |
| SCHEMBL30461437 | 0.81 | SMN1; SMN2 (0.40) | ALDH1A1SMN1; SMN2LMNAGAAHPGD | |
| SCHEMBL21844003 | 0.81 | TP53 (0.43) | ALDH1A1SMN1; SMN2TP53TDP1 | |
| SCHEMBL16750045 | 0.81 | TP53 (0.43) | ALDH1A1SMN1; SMN2TP53TDP1 | |
| SCHEMBL24253076 | 0.81 | TP53 (0.43) | ALDH1A1SMN1; SMN2TP53TDP1 | |
| SCHEMBL21844009 | 0.81 | TP53 (0.43) | ALDH1A1SMN1; SMN2TP53TDP1 | |
| SCHEMBL22697281 | 0.81 | TP53 (0.43) | ALDH1A1SMN1; SMN2LMNAGAAHPGD | |
| SCHEMBL14572731 | 0.81 | TP53 (0.43) | ALDH1A1SMN1; SMN2TP53TDP1 | |
| SCHEMBL19090792 | 0.81 | TP53 (0.43) | ALDH1A1SMN1; SMN2TP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112135812-A | Ketamine derivatives and pharmaceutical compositions thereof | 凯瑞康宁生物工程（武汉）有限公司 | 2020-12-25 | — | — | CN | claimed |
| CN-110917205-A | Substituted nucleosides, nucleotides and analogs thereof | 詹森生物制药有限公司 | 2020-03-27 | — | — | CN | claimed |
| CN-102378580-A | Dipeptide as feedstuff additive | EVONIK DEGUSSA GMBH | 2012-03-14 | — | — | CN | claimed |
| US-20250122149-A1 | KETAMINE DERIVATIVES AND COMPOSITIONS THEREOF | XWPharma Ltd. (KY) | 2025-04-17 | — | — | US | disclosed |
| US-12209060-B2 | Ketamine derivatives and compositions thereof | XWPharma Ltd. (KY) | 2025-01-28 | — | — | US | disclosed |
| US-20240216539-A1 | VECTOR FOR DELIVERING ACTIVE AGENT TO NERVOUS SYSTEM, AND USE THEREOF | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2024-07-04 | — | — | US | disclosed |
| US-20240216539-A1 | VECTOR FOR DELIVERING ACTIVE AGENT TO NERVOUS SYSTEM, AND USE THEREOF | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2024-07-04 | — | — | US | disclosed |
| CN-117881394-A | Pharmaceutical composition and oral dosage form of ketamine derivative | 凯瑞康宁生物工程（武汉）有限公司 | 2024-04-12 | — | — | CN | disclosed |
| US-20230183253-A1 | NANOMATERIAL COMPOSITIONS, SYNTHESIS, AND ASSEMBLY | RHODE ISLAND HOSPITAL | 2023-06-15 | — | — | US | disclosed |
| US-20230143470-A1 | SMALL MOLECULE INHIBITORS OF INFLUENZA HEMAGGLUTININ | NATIONAL INSTITUTES OF HEALTH | 2023-05-11 | — | — | US | disclosed |
| US-20230143470-A1 | SMALL MOLECULE INHIBITORS OF INFLUENZA HEMAGGLUTININ | NATIONAL INSTITUTES OF HEALTH | 2023-05-11 | — | — | US | disclosed |
| EP-2552885-A1 | NEURAMINIDASE INHIBITORS | TSRL, Inc. (US) | 2013-02-06 | — | — | EP | disclosed |
| CN-102378580-A | Dipeptide as feedstuff additive | EVONIK DEGUSSA GMBH | 2012-03-14 | — | — | CN | disclosed |
| WO-2011123856-A1 | NEURAMINIDASE INHIBITORS | TSRL, INC. (US) | 2011-10-06 | — | — | WO | disclosed |
| US-20070072934-A1 | Alkoxy indolinone based protein kinase inhibitors | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-03-29 | — | — | US | disclosed |
| US-6458781-B1 | BLOCKERS CALCIUM CHANNEL ANTAGONISTS FOR STROKES, BRAIN DISORDERS | WARNER-LAMBERT COMPANY | 2002-10-01 | — | — | US | disclosed |
| WO-1999055688-A1 | SUBSTITUTED DIARYLALKYL AMIDES AS CALCIUM CHANNEL ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1999-11-04 | — | — | WO | disclosed |
| US-4447613-A | Pyridyl esters and thiolesters of aminoalkanoic acids | ZOECON CORPORATION (US) | 1984-05-08 | — | — | US | disclosed |
| US-4269981-A | Certain pyridylmethyl esters of formamido-lower-alkanoates and derivatives thereof | ZOECON CORPORATION (US) | 1981-05-26 | — | — | US | disclosed |
| US-4247701-A | Certain pesticidal substituted amino lower-alkanoates or lower-alkano-thioates containing pyridyl in the ester portion | ZOECON CORPORATION (US) | 1981-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12209060-B2 | Ketamine derivatives and compositions thereof | OPRK1, KCNK10, KCNK17 | ALDH1A1 2003/4885SMN1; SMN2 581/4885LMNA 3314/4885 |
| US-20240216539-A1 | VECTOR FOR DELIVERING ACTIVE AGENT TO NERVOUS SYSTEM, AND USE THEREOF | TTR, HAVCR2, PMP22 | ALDH1A1 823/4885SMN1; SMN2 7/4885LMNA 917/4885 |
| US-20250122149-A1 | KETAMINE DERIVATIVES AND COMPOSITIONS THEREOF | OPRK1, KCNK10, KCNK17 | ALDH1A1 2003/4885SMN1; SMN2 581/4885LMNA 3314/4885 |
| US-20230143470-A1 | SMALL MOLECULE INHIBITORS OF INFLUENZA HEMAGGLUTININ | HAVCR2, CD44, ENGASE | ALDH1A1 2185/4885SMN1; SMN2 4875/4885LMNA 2333/4885 |
| US-20070072934-A1 | Alkoxy indolinone based protein kinase inhibitors | PHKG1, MAP3K19, MAP3K20 | ALDH1A1 1969/4885SMN1; SMN2 3450/4885LMNA 3047/4885 |
| US-20230183253-A1 | NANOMATERIAL COMPOSITIONS, SYNTHESIS, AND ASSEMBLY | POLRMT, NT5C3B, CHMP4B | ALDH1A1 3359/4885SMN1; SMN2 292/4885LMNA 210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.