Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | RXFP3 | Q9NSD7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14648049 | 0.90 | L3MBTL1 (0.76) | L3MBTL1SMN1; SMN2POLBHTTGAA | |
| SCHEMBL2176372 | 0.90 | L3MBTL1 (0.76) | L3MBTL1SMN1; SMN2POLBHTTGAA | |
| SCHEMBL13379352 | 0.88 | L3MBTL1 (0.56) | L3MBTL1SMN1; SMN2POLBHTTGAA | |
| SCHEMBL13379349 | 0.88 | L3MBTL1 (0.56) | L3MBTL1SMN1; SMN2POLBGAATP53 | |
| SCHEMBL14662009 | 0.80 | SMN1; SMN2 (0.65) | L3MBTL1SMN1; SMN2POLBHTTTP53 | |
| SCHEMBL18887500 | 0.79 | RXFP3 (0.51) | L3MBTL1SMN1; SMN2POLBHTTGAA | |
| SCHEMBL844889 | 0.79 | RXFP3 (0.51) | L3MBTL1SMN1; SMN2POLBHTTGAA | |
| SCHEMBL5842543 | 0.79 | SMN1; SMN2 (0.55) | L3MBTL1SMN1; SMN2POLBHTTGAA | |
| SCHEMBL6613615 | 0.79 | L3MBTL1 (0.51) | L3MBTL1SMN1; SMN2POLBGAATP53 | |
| SCHEMBL2449353 | 0.76 | L3MBTL1 (1.00) | L3MBTL1SMN1; SMN2POLBHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2328865-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-05-31 | — | — | EP | disclosed |