Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6612380 | 0.88 | L3MBTL1 (0.67) | L3MBTL1CHRM2CHRM1CHRM3POLB | |
| SCHEMBL6610830 | 0.82 | L3MBTL1 (0.42) | L3MBTL1POLBGAA | |
| SCHEMBL2176372 | 0.81 | L3MBTL1 (0.76) | L3MBTL1POLBSMN1; SMN2GAATP53 | |
| SCHEMBL14648049 | 0.81 | L3MBTL1 (0.76) | L3MBTL1POLBSMN1; SMN2GAATP53 | |
| SCHEMBL6611026 | 0.81 | HPGD (0.53) | L3MBTL1POLBSMN1; SMN2GAAATM | |
| SCHEMBL18901976 | 0.79 | L3MBTL1 (0.61) | L3MBTL1POLBSMN1; SMN2GAAHRH3 | |
| SCHEMBL7768685 | 0.78 | SMN1; SMN2 (0.37) | POLBSMN1; SMN2ATMHPGD | |
| SCHEMBL7275276 | 0.76 | DPP4 (0.48) | L3MBTL1POLBSMN1; SMN2GAAATM | |
| SCHEMBL13379352 | 0.75 | L3MBTL1 (0.56) | L3MBTL1POLBSMN1; SMN2GAAHRH3 | |
| SCHEMBL13379349 | 0.75 | L3MBTL1 (0.56) | L3MBTL1POLBSMN1; SMN2GAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1463724-A1 | PYRROLIDONE CARBOXAMIDES | Actelion Pharmaceuticals Ltd. (CH) | 2004-10-06 | — | — | EP | disclosed |
| WO-2003059905-A1 | PYRROLIDONE CARBOXAMIDES | ACTELION PHARMACEUTICALS LTD (CH) | 2003-07-24 | — | — | WO | disclosed |