SCHEMBL1890230

SCHEMBL1890230

[CH2]OCCc1ccc(C(C)(C)C)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.47
SIGMAR1 Q99720 4/20 0.44
MITF O75030 1/20 0.42
GRIA4 P48058 1/20 0.41
APP P05067 1/20 0.41
SLC13A5 Q86YT5 2/20 0.40
ESRRG P62508 2/20 0.40
DAO P14920 1/20 0.40
TSHR P16473 2/20 0.39
ESRRB O95718 1/20 0.39
TP53 P04637 1/20 0.39
ADRA2A P08913 1/20 0.39
ADRA2B P18089 1/20 0.39
ADRA2C P18825 1/20 0.39
ADRA1D P25100 1/20 0.39
HTR1D P28221 1/20 0.39
HTR1B P28222 1/20 0.39
ADRA1A P35348 1/20 0.39
ADRA1B P35368 1/20 0.39
BCHE P06276 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL793588 0.83 KCNH2 (0.50) KCNH2SIGMAR1MITFGRIA4APP
SCHEMBL1890232 0.81 KCNH2 (0.48) KCNH2SIGMAR1MITFGRIA4APP
SCHEMBL7456580 0.79 KCNH2 (0.59) KCNH2SIGMAR1GRIA4SLC13A5ESRRG
SCHEMBL3367885 0.76 ESRRG (0.45) SLC13A5ESRRGESRRBLMNA
SCHEMBL1611459 0.76 KCNH2 (0.52) KCNH2SIGMAR1GRIA4SLC13A5ESRRG
SCHEMBL31573982 0.75 KCNH2 (0.67) KCNH2SIGMAR1MITFGRIA4SLC13A5
SCHEMBL3361817 0.75 KCNH2 (0.43) KCNH2SIGMAR1MITFGRIA4SLC13A5
SCHEMBL1788420 0.75 ESRRG (0.47) KCNH2MITFSLC13A5ESRRGESRRB
SCHEMBL3361820 0.75 TP53 (0.47) KCNH2SIGMAR1MITFGRIA4SLC13A5
SCHEMBL1535645 0.73 KDM4E (0.53) MITFAPPTP53LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7947342-B2 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2011-05-24 US disclosed
US-7854864-B2 Method for manufacturing an optical film having a convexoconcave structure KONICA MINOLTA OPTO, INC. (JP) 2010-12-21 US disclosed
US-20100236713-A1 FILM FOR DISPLAY, POLARIZING PLATE AND MANUFACTURING METHOD THEREOF, AND LIQUID CRYSTAL DISPLAY KONICA MINOLTA OPTO, INC. (JP) 2010-09-23 US disclosed
EP-2012150-A1 POLARIZING PLATE PROTECTION FILM, METHOD FOR PRODUCING THE SAME, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY Konica Minolta Opto, Inc. (JP) 2009-01-07 EP disclosed
EP-2006716-A1 FILM FOR DISPLAY, POLARIZING PLATE AND METHOD FOR PRODUCING THE SAME, AND LIQUID CRYSTAL DISPLAY Konica Minolta Opto, Inc. (JP) 2008-12-24 EP disclosed
US-20080043176-A1 Method of Manufacturing a Polarizing Plate Protective Film, Polarizing Plate Protective Film, Polarizing Plate, and Liquid Crystal Display Device KONICA MINOLTA OPTO, INC. (JP) 2008-02-21 US disclosed
US-20080013173-A1 METHOD OF MANUFACTURING A POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE KONICA MINOLTA OPTO, INC. (JP) 2008-01-17 US disclosed
US-20070252293-A1 METHOD FOR MANUFACTURING AN OPTICAL FILM HAVING A CONVEXOCONCAVE STRUCTURE, OPTICAL FILM, WIRE GRID POLARIZER AND RETARDATION FILM KONICA MINOLTA OPTO, INC. (JP) 2007-11-01 US disclosed
US-20070254115-A1 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2007-11-01 US disclosed
US-20070227652-A1 FILM FOR DISPLAY, POLARIZING PLATE AND MANUFACTURING METHOD THEREOF, AND LIQUID CRYSTAL DISPLAY KONICA MINOLTA OPTO, INC. (JP) 2007-10-04 US disclosed