Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 4/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17811538 | 0.83 | MAOA (0.47) | MAOAMAOBSIGMAR1PLK1AR | |
| SCHEMBL19754081 | 0.73 | SIGMAR1 (0.42) | SIGMAR1 | |
| SCHEMBL19308405 | 0.68 | SIGMAR1 (0.37) | SIGMAR1 | |
| SCHEMBL827203 | 0.68 | SIGMAR1 (0.41) | SIGMAR1 | |
| SCHEMBL8093324 | 0.66 | SIGMAR1 (0.41) | SIGMAR1 | |
| SCHEMBL8099732 | 0.66 | SIGMAR1 (0.41) | SIGMAR1 | |
| SCHEMBL8095795 | 0.66 | SIGMAR1 (0.41) | SIGMAR1 | |
| SCHEMBL8087655 | 0.66 | SIGMAR1 (0.41) | SIGMAR1 | |
| SCHEMBL8095635 | 0.66 | SIGMAR1 (0.41) | SIGMAR1 | |
| SCHEMBL8100525 | 0.66 | SIGMAR1 (0.41) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3024855-B1 | POLYMERISATION INITIATORS | TRINSEO EUROPE GMBH (CH) | 2017-05-31 | — | — | EP | disclosed |