Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.68 |
| ▸ | VDR | P11473 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | CDC25A | P30304 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | PGR | P06401 | 1/20 | 0.68 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.68 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.68 |
| ▸ | DRD3 | P35462 | 1/20 | 0.68 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1890289 | 0.87 | MEN1 (0.71) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL7516578 | 0.86 | MEN1 (0.81) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL11129087 | 0.86 | MEN1 (0.81) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL10888072 | 0.85 | ADORA3 (0.73) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL3727604 | 0.85 | ADORA3 (0.73) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL9813893 | 0.85 | MAPT (0.71) | MAPTADORA3VDRSMN1; SMN2PGR | |
| SCHEMBL7518557 | 0.84 | MEN1 (0.69) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL22577759 | 0.83 | MAPT (0.77) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL11681021 | 0.83 | ADORA3 (0.76) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL378182 | 0.83 | MAPT (0.77) | MEN1KMT2AMAPTALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080064668-A1 | 1,3-Diacylated, 26,27-Alkyl/Haloakyl Vitamin D3 Compounds and Methods of Use Thereof | BIOXELL S.P.A. (IT) | 2008-03-13 | — | — | US | disclosed |
| US-5039671-A | Bone disorders; calcium or phosphorus inbalance | HOFFMANN-LA ROCHE INC. (US) | 1991-08-13 | — | — | US | disclosed |
| US-4906785-A | Novel trifluorinated vitamin D3 intermediates | HOFFMANN-LA ROCHE INC. (US) | 1990-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064668-A1 | 1,3-Diacylated, 26,27-Alkyl/Haloakyl Vitamin D3 Compounds and Methods of Use Thereof | CYP24A1, VDR, CYP2R1 | MEN1 1616/4885KMT2A 3681/4885MAPT 4687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.