Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18903922 | 0.79 | TP53 (0.44) | L3MBTL1ALDH1A1MAPTKDM4EHTT | |
| SCHEMBL16509619 | 0.76 | L3MBTL1 (0.71) | L3MBTL1ALDH1A1KDM4EHTTPOLB | |
| SCHEMBL25379946 | 0.74 | SMN1; SMN2 (0.53) | L3MBTL1ALDH1A1MAPTKDM4EHTT | |
| SCHEMBL50204 | 0.72 | GAA (0.61) | L3MBTL1ALDH1A1MAPTKDM4EHTT | |
| SCHEMBL18904084 | 0.69 | MAPT (0.48) | ALDH1A1MAPTKDM4EHTTTSHR | |
| SCHEMBL18903943 | 0.69 | HRH3 (0.43) | L3MBTL1ALDH1A1KDM4EHTTLMNA | |
| SCHEMBL18903780 | 0.68 | NMT1 (0.42) | L3MBTL1MAPTKDM4EHTTTSHR | |
| SCHEMBL18903996 | 0.68 | NMT1 (0.51) | — | |
| SCHEMBL18904119 | 0.68 | NMT1 (0.44) | L3MBTL1ALDH1A1KDM4EHTTPOLB | |
| SCHEMBL18903979 | 0.68 | SMN1; SMN2 (0.37) | ALDH1A1KDM4EHTTTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2980076-B1 | Pyrazolyl derivatives | UNIV DUNDEE (GB) | 2017-05-31 | — | — | EP | disclosed |