Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 14/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | LYPLA1 | O75608 | 1/20 | 0.31 |
| ▸ | LYPLA2 | O95372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16503069 | 0.80 | LMNA (0.59) | NMT1LMNAHTTSMN1; SMN2 | |
| SCHEMBL16503066 | 0.77 | LMNA (0.60) | NMT1LMNAHTTSMN1; SMN2 | |
| SCHEMBL16502968 | 0.70 | NMT1 (0.42) | NMT1LMNAHTTSMN1; SMN2HTR7 | |
| SCHEMBL18903979 | 0.70 | SMN1; SMN2 (0.37) | LMNAHTTSMN1; SMN2 | |
| SCHEMBL18904200 | 0.69 | NMT1 (0.53) | NMT1HTR7HTR1A | |
| SCHEMBL10263378 | 0.69 | KCNH2 (0.38) | CYP1A2CYP2C19LYPLA1LYPLA2 | |
| SCHEMBL18903943 | 0.69 | HRH3 (0.43) | NMT1LMNAHTTSMN1; SMN2 | |
| SCHEMBL18904018 | 0.69 | NMT1 (0.65) | NMT1 | |
| SCHEMBL18903949 | 0.68 | HTT (0.38) | NMT1LMNAHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL18904027 | 0.68 | MAPT (0.50) | NMT1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2980076-B1 | Pyrazolyl derivatives | UNIV DUNDEE (GB) | 2017-05-31 | — | — | EP | disclosed |