Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.47 |
| ▸ | NMT1 | P30419 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18904151 | 0.80 | NPC1 (0.42) | MAPTMEN1KMT2AGAATP53 | |
| SCHEMBL18904188 | 0.75 | KMT2A (0.46) | MAPTMEN1KMT2ACA12CA9 | |
| SCHEMBL11838896 | 0.72 | MAPT (0.84) | MAPTMEN1KMT2AGAABLM | |
| SCHEMBL18904219 | 0.72 | NMT1 (0.55) | NMT1 | |
| SCHEMBL18903961 | 0.72 | NMT1 (0.52) | MAPTMEN1KMT2ANMT1RAB9A | |
| SCHEMBL8082984 | 0.71 | MAPT (0.82) | MAPTMEN1KMT2AGAABLM | |
| SCHEMBL16509534 | 0.70 | NMT1 (0.60) | NMT1L3MBTL1SMN1; SMN2 | |
| SCHEMBL18903977 | 0.69 | NMT1 (0.46) | NMT1L3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4667164 | 0.69 | MAPT (1.00) | MAPTMEN1KMT2AGAABLM | |
| SCHEMBL18904208 | 0.68 | NMT1 (0.39) | NMT1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2980076-B1 | Pyrazolyl derivatives | UNIV DUNDEE (GB) | 2017-05-31 | — | — | EP | disclosed |