Known targets — ChEMBL curated mechanism
823298382338688239847Rdl1Rdl2Rdl3
The experimentally established mechanism targets of Lindane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lindane SCHEMBL21246973 | 0.83 | LMNA (0.39) | LMNANPC1CYP1A2 | |
| Methoxymethane SCHEMBL108410 | 0.80 | LMNA (0.43) | LMNANPC1CYP1A2 | |
| Methyl Alcohol SCHEMBL11594237 | 0.76 | LMNA (0.53) | LMNANPC1CYP1A2 | |
| Methyl Alcohol SCHEMBL8093100 | 0.76 | LMNA (0.53) | LMNANPC1CYP1A2 | |
| Methyl Alcohol SCHEMBL1535535 | 0.76 | LMNA (0.53) | LMNANPC1CYP1A2 | |
| Methyl Alcohol SCHEMBL7168433 | 0.76 | LMNA (0.53) | LMNANPC1CYP1A2 | |
| Urea SCHEMBL11581340 | 0.72 | CYP1A2 (0.42) | LMNANPC1CYP1A2 | |
| Methoxymethane SCHEMBL8162873 | 0.71 | LMNA (0.43) | LMNANPC1CYP1A2 | |
| Lindane SCHEMBL10698494 | 0.70 | ALDH1A1 (0.38) | LMNACYP1A2 | |
| Methoxymethane SCHEMBL3858154 | 0.69 | HSP90AB1 (0.50) | LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9169409-B2 | Ink composition for imprint lithography and roll printing | LG DISPLAY CO., LTD. (KR) | 2015-10-27 | — | — | US | disclosed |
| US-20150133582-A1 | INK COMPOSITION FOR IMPRINT LITHOGRAPHY AND ROLL PRINTING | LG DISPLAY CO., LTD. (KR) | 2015-05-14 | — | — | US | disclosed |
| US-20110224335-A1 | INK COMPOSITION AND METHOD OF FABRICATING LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME | KIM SUNG-HEE | 2011-09-15 | — | — | US | disclosed |
| US-7935552-B2 | Ink composition and method of fabricating liquid crystal display device using the same | LG DISPLAY CO., LTD. (KR) | 2011-05-03 | — | — | US | disclosed |
| US-20100120181-A1 | INK COMPOSITION AND METHOD OF FABRICATING LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME | LG DISPLAY CO., LTD. (KR) | 2010-05-13 | — | — | US | disclosed |