Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | GALR3 | O60755 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18905266 | 0.83 | AKR1C3 (0.39) | AKR1C2SMN1; SMN2CYP1A2LMNAAOC3 | |
| SCHEMBL15115428 | 0.82 | ACACB (0.41) | FFAR1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL18910992 | 0.82 | ACACB (0.41) | FFAR1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL1050122 | 0.80 | TAAR1 (0.53) | SMN1; SMN2L3MBTL1CYP1A2CYP2C19TAAR1 | |
| SCHEMBL1338710 | 0.78 | AKR1C2 (0.42) | IDO1AKR1C2AKR1C1L3MBTL1ADRB2 | |
| SCHEMBL9069719 | 0.77 | TDP1 (0.48) | IDO1AKR1C2AKR1C1L3MBTL1TAAR1 | |
| SCHEMBL18905328 | 0.77 | MMP12 (0.44) | FFAR1AKR1C2MMP12L3MBTL1LMNA | |
| SCHEMBL8750369 | 0.76 | HTR2A (0.53) | LMNAHIF1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8750498 | 0.76 | HTR2A (0.53) | LMNAHIF1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18905279 | 0.75 | LMNA (0.40) | AKR1C2L3MBTL1CYP2D6ADRB2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170154766-A1 | SILICON-CONTAINING CONDENSATE, COMPOSITION FOR FORMING A SILICON-CONTAINING RESIST UNDER LAYER FILM, AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-06-01 | — | — | US | disclosed |