Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.59 |
| ▸ | LTA4H | P09960 | 4/20 | 0.53 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24533728 | 0.90 | HRH3 (0.61) | HRH3NR5A1CYP3A4SMN1; SMN2GAA | |
| SCHEMBL25575420 | 0.88 | HRH3 (0.52) | HRH3LTA4HNR5A1ALDH1A1 | |
| SCHEMBL18910998 | 0.85 | ALDH1A1 (0.63) | HRH3LTA4HNR5A1ALDH1A1CYP3A4 | |
| SCHEMBL21483751 | 0.85 | HRH3 (0.56) | HRH3ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL18905500 | 0.85 | HRH3 (0.56) | HRH3ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL19687568 | 0.84 | SMN1; SMN2 (0.66) | HRH3ALDH1A1CYP3A4SMN1; SMN2GAA | |
| SCHEMBL24533712 | 0.84 | HRH3 (0.55) | HRH3ALDH1A1CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL11547049 | 0.83 | NQO1 (0.61) | HRH3LTA4HALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL4738149 | 0.83 | SMN1; SMN2 (0.58) | LTA4HNR5A1ALDH1A1CYP3A4TSHR | |
| SCHEMBL9593021 | 0.83 | HRH3 (0.57) | HRH3LTA4HNR5A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185363-A | Administering for treatment of inflammatory diseases | ABBOTT LABORATORIES (US) | 1993-02-09 | — | — | US | disclosed |
| EP-0292699-A2 | Urea based lipoxygenase inhibiting compounds | ABBOTT LABORATORIES (US) | 1988-11-30 | — | — | EP | disclosed |