SCHEMBL1890668

SCHEMBL1890668

COc1ccc2c(c1)C(C)(C)C1(C=Cc3cc([N+](=O)[O-])ccc3O1)N2C

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.68
KMT2A Q03164 3/20 0.68
GFER P55789 1/20 0.68
MAPT P10636 7/20 0.51
GAA P10253 4/20 0.51
LMNA P02545 4/20 0.51
SMN1; SMN2 Q16637 4/20 0.51
RECQL P46063 3/20 0.51
TDP1 Q9NUW8 3/20 0.51
THRB P10828 3/20 0.51
PLIN1 O60240 1/20 0.51
PKM P14618 1/20 0.51
TSHR P16473 1/20 0.51
PLIN5 Q00G26 1/20 0.51
ABHD5 Q8WTS1 1/20 0.51
NPSR1 Q6W5P4 2/20 0.50
ALPG P10696 1/20 0.50
TP53 P04637 1/20 0.50
ALOX15 P16050 1/20 0.50
HSD17B10 Q99714 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8680133 0.90 MEN1 (0.80) MEN1KMT2AGFERMAPTGAA
SCHEMBL20985941 0.87 MAPT (0.56) MEN1KMT2AGFERMAPTGAA
SCHEMBL8682035 0.86 MEN1 (0.71) MEN1KMT2AGFERMAPTGAA
SCHEMBL29823427 0.86 MAPT (0.54) MEN1KMT2AGFERMAPTGAA
SCHEMBL4580154 0.85 MEN1 (0.70) MEN1KMT2AGFERMAPTGAA
SCHEMBL8680208 0.85 MEN1 (0.70) MEN1KMT2AGFERMAPTGAA
SCHEMBL8684928 0.85 MEN1 (0.70) MEN1KMT2AGFERMAPTGAA
SCHEMBL8680190 0.85 MEN1 (0.70) MEN1KMT2AGFERMAPTGAA
SCHEMBL38652522 0.85 MEN1 (0.70) MEN1KMT2AGFERMAPTGAA
SCHEMBL8682556 0.85 MEN1 (0.52) MEN1KMT2AGFERMAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9857882-B2 Pointing display device DONGWOO FINE-CHEM CO., LTD. (KR) 2018-01-02 US claimed
US-5759729-A A DRY TONER COMPRISING A RESIN, PHOTOCHROMATIC SPIROPYRAN, -OXAZINE OR -THIOPYRAN DYE AND A CHARGE CONTROL AGENT;ELECTROGRAPHY; XEROGRAPHY XEROX CORPORATION (US) 1998-06-02 US claimed
US-4225661-A DIAZO RESIN LAYER, PHOTOCHROMIC DYE AND ADDITION POLYMER OVERLAYER THE RICHARDSON COMPANY (US) 1980-09-30 US claimed
US-11352554-B2 Photochromic water harvesting platform WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC (US) 2022-06-07 US disclosed
US-10754211-B2 Display device and manufacturing method thereof SAMSUNG DISPLAY CO., LTD. (KR) 2020-08-25 US disclosed
US-10381134-B2 Strain gauge polymer comprising photochromic colorant XEROX CORPORATION (US) 2019-08-13 US disclosed
US-10381134-B2 Strain gauge polymer comprising photochromic colorant XEROX CORPORATION (US) 2019-08-13 US disclosed
US-20190153306-A1 Photochromic Water Harvesting Platform WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC (US) 2019-05-23 US disclosed
US-10022996-B2 Infrared sensitive color-forming composition, infrared curable color-forming composition, lithographic printing plate precursor and plate making method FUJIFILM CORPORATION (JP) 2018-07-17 US disclosed
EP-3299873-A1 DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF Samsung Display Co., Ltd. (KR) 2018-03-28 EP disclosed
US-20180081225-A1 DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-22 US disclosed
EP-1179558-A1 METHOD OF MODIFYING SURFACE LAYER OF MOLDED RESIN AND APPARATUS FOR MODIFYING SURFACE LAYER OF MOLDED RESIN Japan as represented by Secretary of Agency of Industrial Science and Technology (JP) 2002-02-13 EP disclosed
US-6084702-A Thermochromic devices PLEOTINT, L.L.C. (US) 2000-07-04 US disclosed
US-5759729-A A DRY TONER COMPRISING A RESIN, PHOTOCHROMATIC SPIROPYRAN, -OXAZINE OR -THIOPYRAN DYE AND A CHARGE CONTROL AGENT;ELECTROGRAPHY; XEROGRAPHY XEROX CORPORATION (US) 1998-06-02 US disclosed
US-5710420-A Method for embedding and recovering machine-readable information XEROX CORPORATION (US) 1998-01-20 US disclosed
US-5633109-A Ink compositions with liposomes containing photochromic compounds XEROX CORPORATION (US) 1997-05-27 US disclosed
US-5593486-A Photochromic hot melt ink compositions XEROX CORPORATION (US) 1997-01-14 US disclosed
US-5551973-A LIQUID CRYSTAL GEL PHASE, MICROEMULSION PHASE XEROX CORPORATION (US) 1996-09-03 US disclosed
US-4225661-A DIAZO RESIN LAYER, PHOTOCHROMIC DYE AND ADDITION POLYMER OVERLAYER THE RICHARDSON COMPANY (US) 1980-09-30 US disclosed
US-3933509-A Photo-polymerizable composition containing an acid salt of an indolinobenzospiropyran FUJI PHOTO FILM CO., LTD. (JA) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10381134-B2 Strain gauge polymer comprising photochromic colorant CABLES1, MAPK11, MARK4 MEN1 3296/4885KMT2A 2445/4885GFER 1432/4885
US-11352554-B2 Photochromic water harvesting platform AQP1, AQP3, BLM MEN1 4705/4885KMT2A 2502/4885GFER 1610/4885
US-20190153306-A1 Photochromic Water Harvesting Platform AQP1, AQP3, BLM MEN1 4705/4885KMT2A 2502/4885GFER 1610/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.