Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18906767 | 0.82 | HCRTR1 (0.43) | ALDH1A1KDM4EHPGDTHRBMAPT | |
| SCHEMBL28364130 | 0.81 | AHR (0.52) | ALDH1A1KDM4EHPGDTHRBMAPT | |
| SCHEMBL17444569 | 0.78 | KDM4E (0.70) | ALDH1A1KDM4EHPGDTHRBMAPT | |
| SCHEMBL18263044 | 0.76 | RAB9A (0.57) | ALDH1A1KDM4EHPGDTHRBMAPT | |
| SCHEMBL4374342 | 0.74 | ALDH1A1 (0.68) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL17444608 | 0.72 | KDM4E (0.65) | ALDH1A1KDM4EHPGDTHRBMAPT | |
| SCHEMBL18889429 | 0.71 | AHR (0.40) | ALDH1A1KDM4EHPGDTHRBMAPT | |
| SCHEMBL9809027 | 0.71 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL5049780 | 0.71 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL18941237 | 0.71 | KMT2A (0.66) | ALDH1A1KDM4EHPGDTHRBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170152226-A1 | FUNCTIONALISED AND SUBSTITUTED INDOLES AS ANTI-CANCER AGENTS | Novogen ltd (AU) | 2017-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170152226-A1 | FUNCTIONALISED AND SUBSTITUTED INDOLES AS ANTI-CANCER AGENTS | TPM3, TPM4, TNNI3 | ALDH1A1 1176/4885KDM4E 1403/4885HPGD 1136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.