SCHEMBL18907487

SCHEMBL18907487

c1ccc2cc(-c3ccc(-c4cc5c6ccccc6c(-c6cccc7sc8ccccc8c67)cc5c5ccccc45)cc3)ccc2c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR5 Q9H228 8/20 0.39
S1PR4 O95977 6/20 0.39
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
HSD17B1 P14061 1/20 0.36
HSD17B2 P37059 1/20 0.36
BRDT Q58F21 1/20 0.35
ALOX5 P09917 2/20 0.35
GSTP1 P09211 1/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA9 Q16790 2/20 0.34
CA12 O43570 1/20 0.34
ALDH1A1 P00352 2/20 0.33
HPGD P15428 2/20 0.33
TSHR P16473 2/20 0.33
MAPK1 P28482 2/20 0.33
CASP1 P29466 2/20 0.33
HIF1A Q16665 2/20 0.33
HSD17B10 Q99714 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18907461 0.95 S1PR5 (0.43) S1PR5S1PR4HSD17B1HSD17B2BRDT
SCHEMBL18907535 0.88 F9 (0.41) BRDTALOX5CA1CA2CA9
SCHEMBL13408905 0.85 S1PR5 (0.42) S1PR5S1PR4HSD17B1HSD17B2BRDT
SCHEMBL18907547 0.84 F9 (0.43) BRDTALOX5ALDH1A1HPGDTSHR
SCHEMBL18907533 0.84 ALOX5 (0.49) S1PR5S1PR4ESR1ESR2HSD17B1
SCHEMBL23448786 0.83 S1PR5 (0.35) S1PR5S1PR4ESR1ESR2HSD17B1
SCHEMBL25137856 0.83 S1PR5 (0.38) S1PR5S1PR4ESR1ESR2HSD17B1
SCHEMBL20650708 0.83 S1PR5 (0.40) S1PR5S1PR4ESR1ESR2HSD17B1
SCHEMBL18907483 0.82 GSTP1 (0.40) S1PR5S1PR4ESR1ESR2HSD17B1
SCHEMBL18907485 0.82 ALDH1A1 (0.41) S1PR5S1PR4ESR1ESR2HSD17B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210336144-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2021-10-28 US disclosed
US-11018304-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2021-05-25 US disclosed
US-20200259086-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2020-08-13 US disclosed
US-10665789-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2020-05-26 US disclosed
US-20170155050-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-01 US disclosed
US-20170155050-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-01 US disclosed