SCHEMBL18907461

SCHEMBL18907461

c1ccc2cc(-c3cc4c5ccccc5c(-c5cccc6sc7ccccc7c56)cc4c4ccccc34)ccc2c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR5 Q9H228 9/20 0.43
S1PR4 O95977 7/20 0.43
GSTP1 P09211 1/20 0.39
ALOX5 P09917 1/20 0.39
HDAC4 P56524 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
BRDT Q58F21 1/20 0.37
GPR3 P46089 1/20 0.35
ALDH1A1 P00352 3/20 0.35
HPGD P15428 3/20 0.35
TSHR P16473 2/20 0.35
MAPK1 P28482 2/20 0.35
CASP1 P29466 2/20 0.35
HIF1A Q16665 2/20 0.35
HSD17B10 Q99714 2/20 0.35
TP53 P04637 1/20 0.35
CASP7 P55210 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
HSD17B1 P14061 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18907487 0.95 S1PR5 (0.39) S1PR5S1PR4GSTP1ALOX5BRDT
SCHEMBL13408905 0.90 S1PR5 (0.42) S1PR5S1PR4GSTP1ALOX5HDAC4
SCHEMBL18907535 0.84 F9 (0.41) ALOX5BRDTGPR3ALDH1A1HPGD
SCHEMBL18907473 0.84 GPR3 (0.41) ALOX5BRDTGPR3ALDH1A1HPGD
SCHEMBL18907547 0.84 F9 (0.43) ALOX5BRDTGPR3ALDH1A1HPGD
SCHEMBL18907536 0.84 ALDH1A1 (0.51) ALOX5BRDTGPR3ALDH1A1HPGD
SCHEMBL22707031 0.84 S1PR5 (0.44) S1PR5S1PR4GSTP1ALOX5HDAC4
SCHEMBL22707527 0.83 S1PR5 (0.43) S1PR5S1PR4GSTP1ALOX5HDAC4
SCHEMBL18907455 0.83 ALOX5 (0.55) S1PR5S1PR4GSTP1ALOX5HDAC4
SCHEMBL18907451 0.82 GPR3 (0.44) S1PR5S1PR4GSTP1ALOX5HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210336144-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2021-10-28 US disclosed
US-11018304-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2021-05-25 US disclosed
US-20200259086-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2020-08-13 US disclosed
US-10665789-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2020-05-26 US disclosed
US-20170155050-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-01 US disclosed
US-20170155050-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-01 US disclosed