Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18908200 | 1.00 | HTR2A (0.38) | HTR2AHTR2CDRD4SIGMAR1KDM1A | |
| SCHEMBL18908176 | 1.00 | HTR2A (0.38) | HTR2AHTR2CDRD4SIGMAR1KDM1A | |
| SCHEMBL18820764 | 1.00 | HTR2A (0.38) | HTR2AHTR2CDRD4SIGMAR1KDM1A | |
| SCHEMBL21570596 | 0.85 | NAAA (0.39) | SIGMAR1ACACBNAAAALDH1A1CYP2C19 | |
| SCHEMBL18908199 | 0.83 | PTGDR2 (0.36) | DRD4SIGMAR1ACACBSMN1; SMN2FFAR4 | |
| SCHEMBL18908173 | 0.82 | ACACB (0.35) | HTR2AHTR2CDRD4ACACBSMN1; SMN2 | |
| SCHEMBL18908198 | 0.82 | ACACB (0.35) | HTR2AHTR2CDRD4ACACBSMN1; SMN2 | |
| SCHEMBL18820760 | 0.82 | ACACB (0.35) | HTR2AHTR2CDRD4ACACBSMN1; SMN2 | |
| SCHEMBL22994419 | 0.78 | ACACA (0.43) | HTR2AHTR2CACACB | |
| SCHEMBL22994452 | 0.78 | ACACA (0.43) | HTR2AHTR2CACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017091617-A1 | TRIAZOLE ACC INHIBITORS AND USES THEREOF | GILEAD APOLLO, LLC (US) | 2017-06-01 | — | — | WO | disclosed |