Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18908182 | 0.85 | HTR2A (0.38) | NAAACYP2C19ALDH1A1SIGMAR1ACACB | |
| SCHEMBL18820764 | 0.85 | HTR2A (0.38) | NAAACYP2C19ALDH1A1SIGMAR1ACACB | |
| SCHEMBL18908176 | 0.85 | HTR2A (0.38) | NAAACYP2C19ALDH1A1SIGMAR1ACACB | |
| SCHEMBL18908200 | 0.85 | HTR2A (0.38) | NAAACYP2C19ALDH1A1SIGMAR1ACACB | |
| SCHEMBL21570671 | 0.85 | AGTR1 (0.37) | ACACAACACBPOLBHTTNPSR1 | |
| SCHEMBL21570698 | 0.84 | ACACA (0.42) | ACACAACACBPOLBHTTNPSR1 | |
| SCHEMBL24404214 | 0.81 | ACACA (0.42) | ACACAACACBPOLBHTTNPSR1 | |
| SCHEMBL22869926 | 0.81 | ACACA (0.42) | ACACAACACBPOLBHTTNPSR1 | |
| SCHEMBL24404173 | 0.81 | ACACA (0.42) | ACACAACACBPOLBHTTNPSR1 | |
| SCHEMBL22869916 | 0.81 | ACACA (0.42) | ACACAACACBPOLBHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3571205-B1 | THIENOPYRIMIDINE DERIVATIVE AND USE THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO LTD (CN) | 2023-08-30 | — | — | EP | disclosed |
| US-10759812-B2 | Thienopyrimidine derivative and use thereof in medicine | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2020-09-01 | — | — | US | disclosed |
| US-20190352311-A1 | THIENOPYRIMIDINE DERIVATIVE AND USE THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2019-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190352311-A1 | THIENOPYRIMIDINE DERIVATIVE AND USE THEREOF IN MEDICINE | ACACA, ACACB, PC | NAAA 876/4885CA1 4178/4885CA2 3776/4885 |
| US-10759812-B2 | Thienopyrimidine derivative and use thereof in medicine | ACACA, ACACB, PC | NAAA 876/4885CA1 4178/4885CA2 3776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.