SCHEMBL1890883

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1893869	0.89	PARP1 (0.61)	PARP1CYP1A2ALDH1A1RAB9ANPC1
	SCHEMBL12662417	0.88	MGAM (0.40)	ALDH1A1RAB9ANPC1SMN1; SMN2GAA
	SCHEMBL12662406	0.88	KCNMA1 (0.50)	CYP1A2ALDH1A1RAB9ANPC1SMN1; SMN2
	SCHEMBL1888343	0.88	MGAM (0.42)	ALDH1A1RAB9ANPC1SMN1; SMN2GAA
	SCHEMBL12662391	0.84	PARP1 (0.48)	PARP1ALDH1A1RAB9ANPC1SMN1; SMN2
	SCHEMBL12662386	0.84	PARP1 (0.52)	PARP1RAB9ANPC1HDAC3HDAC7
	SCHEMBL13256162	0.84	CYP1A2 (0.46)	PARP1CYP1A2ALDH1A1RAB9ANPC1
	SCHEMBL12662384	0.83	NPC1 (0.50)	PARP1RAB9ANPC1PTGESMEN1
	SCHEMBL12662492	0.83	PARP1 (0.48)	PARP1CYP1A2ALDH1A1RAB9ANPC1
	SCHEMBL12662388	0.82	PTGES (0.53)	PARP1ALDH1A1RAB9ANPC1HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.