Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | NGFR | P08138 | 1/20 | 0.38 |
| ▸ | CYP4Z1 | Q86W10 | 4/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | CDC25A | P30304 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RGS12 | O14924 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7488947 | 0.87 | ASAH1 (0.44) | ASAH1TDP1CYP4Z1CES1CDC25A | |
| SCHEMBL18908878 | 0.87 | CYP1A2 (0.34) | ASAH1TDP1EPHX1NTRK1NGFR | |
| SCHEMBL7493436 | 0.82 | STAT3 (0.42) | ASAH1TDP1CYP4Z1CES1CDC25A | |
| SCHEMBL11590564 | 0.82 | TDP1 (0.60) | ASAH1TDP1NTRK1NGFRSIRT1 | |
| SCHEMBL27387263 | 0.81 | ASAH1 (0.59) | ASAH1CYP4Z1CES1CDC25ANAAA | |
| SCHEMBL4950343 | 0.80 | ASAH1 (0.56) | ASAH1TDP1CYP4Z1CES1CDC25A | |
| SCHEMBL7488405 | 0.80 | MEN1 (0.50) | TDP1SIRT1CES1CDC25AL3MBTL1 | |
| SCHEMBL18908883 | 0.80 | ASAH1 (0.39) | ASAH1TDP1CYP4Z1CES1CDC25A | |
| SCHEMBL7484646 | 0.80 | MEN1 (0.50) | TDP1SIRT1CES1CDC25AL3MBTL1 | |
| SCHEMBL19630393 | 0.77 | TDP1 (0.61) | TDP1NTRK1NGFRSIRT1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9952521-B2 | Naphthalenedicarboximide derivative and electrophotographic photosensitive member | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2018-04-24 | — | — | US | disclosed |
| US-20170153560-A1 | NAPHTHALENEDICARBOXIMIDE DERIVATIVE AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2017-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170153560-A1 | NAPHTHALENEDICARBOXIMIDE DERIVATIVE AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | CRY1, CRY2, CCNT1 | ASAH1 2110/4885TDP1 2267/4885EPHX1 3038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.