Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 1/20 | 0.59 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.49 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | CDC25A | P30304 | 1/20 | 0.46 |
| ▸ | CYP4Z1 | Q86W10 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4950343 | 0.98 | ASAH1 (0.56) | ASAH1NR1H2NR1H3CES1CDC25A | |
| SCHEMBL30501189 | 0.86 | SIGMAR1 (0.44) | ASAH1ALDH1A1CYP1A2ACHE | |
| SCHEMBL7488947 | 0.86 | ASAH1 (0.44) | ASAH1CES1CDC25ACYP4Z1ALDH1A1 | |
| SCHEMBL13134034 | 0.85 | CYP1A2 (0.47) | ASAH1NR1H2NR1H3ALDH1A1CYP1A2 | |
| SCHEMBL11590564 | 0.84 | TDP1 (0.60) | ASAH1ALDH1A1 | |
| SCHEMBL28876218 | 0.83 | CYP1A2 (0.42) | ASAH1ALDH1A1CYP1A2ACHE | |
| SCHEMBL18908877 | 0.81 | ASAH1 (0.42) | ASAH1CES1CDC25ACYP4Z1ALDH1A1 | |
| SCHEMBL7493436 | 0.81 | STAT3 (0.42) | ASAH1CES1CDC25ACYP4Z1 | |
| SCHEMBL22649169 | 0.81 | CYP1A2 (0.43) | ASAH1ALDH1A1CYP1A2ACHE | |
| SCHEMBL8227448 | 0.81 | CYP1A2 (0.43) | ASAH1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1067052-A | The diaminophthalimides and the analogue thereof that replace | CIBA GEIGY AG (CH) | 1992-12-16 | — | — | CN | claimed |
| CN-1067052-A | The diaminophthalimides and the analogue thereof that replace | CIBA GEIGY AG (CH) | 1992-12-16 | — | — | CN | disclosed |