Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13188548 | 0.96 | ATM (0.58) | ATML3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL12446607 | 0.94 | ATM (0.56) | ATML3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL20693526 | 0.94 | ATM (0.56) | ATML3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL13188549 | 0.83 | TDP1 (0.45) | ATML3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL17057244 | 0.83 | KMT2A (0.45) | ATMTDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL12435378 | 0.83 | ATM (0.65) | ATML3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL4566692 | 0.82 | ATM (0.63) | ATML3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL2388012 | 0.82 | ALDH1A1 (0.38) | ATML3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL3732338 | 0.82 | ALDH1A1 (0.38) | ATML3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL12352492 | 0.82 | TPSAB1 (0.41) | ATMTDP1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017089390-A1 | JANUS KINASES INHIBITORS, COMPOSITIONS THEREOF AND USE THEREOF | F. HOFFMANN-LA ROCHE AG (CH) | 2017-06-01 | — | — | WO | disclosed |