Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.55 |
| ▸ | F10 | P00742 | 6/20 | 0.54 |
| ▸ | F5 | P12259 | 1/20 | 0.54 |
| ▸ | BRSK2 | Q8IWQ3 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | DHODH | Q02127 | 3/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | RPA1 | P27694 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18683536 | 0.85 | F10 (0.53) | MALT1F10F5BRSK2ALDH1A1 | |
| SCHEMBL9201508 | 0.77 | RPA1 (0.70) | MALT1PTGS2RPA1FAAH | |
| SCHEMBL5641582 | 0.77 | F10 (0.56) | F10F5BRSK2DHODH | |
| SCHEMBL7056604 | 0.77 | ALDH1A1 (0.54) | MALT1ALDH1A1LMNAHTTDHODH | |
| SCHEMBL6763496 | 0.76 | F10 (0.53) | F10F5BRSK2KLKB1DHODH | |
| SCHEMBL6173361 | 0.75 | RPA1 (0.67) | MALT1ALDH1A1LMNAHTTDHODH | |
| SCHEMBL6493037 | 0.75 | RPA1 (0.55) | MALT1ALDH1A1LMNAHTTDHODH | |
| SCHEMBL6173677 | 0.75 | RPA1 (0.62) | MALT1ALDH1A1LMNAHTTDHODH | |
| SCHEMBL6533973 | 0.73 | MALT1 (0.57) | MALT1ALDH1A1GAA | |
| SCHEMBL5644448 | 0.73 | F10 (0.57) | F10F5BRSK2DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9938272-B2 | Hydrazine compound as blood coagulation factor Xa inhibitor | NORTH CHINA PHARMACEUTICAL COMPANY., LTD. (CN) | 2018-04-10 | — | — | US | disclosed |
| US-20170152259-A1 | HYDRAZINE COMPOUND AS BLOOD COAGULATION FACTOR Xa INHIBITOR | NORTH CHINA PHARMACEUTICAL COMPANY., LTD. (CN) | 2017-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170152259-A1 | HYDRAZINE COMPOUND AS BLOOD COAGULATION FACTOR Xa INHIBITOR | F12, F10, F11 | MALT1 4510/4885F10 2/4885F5 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.