Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21980409 | 1.00 | ACACB (0.45) | ACACBACACA | |
| SCHEMBL29354548 | 1.00 | ACACB (0.45) | ACACBACACA | |
| SCHEMBL30901794 | 1.00 | ACACB (0.45) | ACACBACACA | |
| SCHEMBL18908171 | 0.87 | ACACB (0.44) | ACACBACACA | |
| SCHEMBL14945397 | 0.86 | ACACB (0.47) | ACACBACACA | |
| SCHEMBL14945398 | 0.86 | ACACB (0.47) | ACACBACACA | |
| SCHEMBL21816549 | 0.86 | ACACB (0.47) | ACACBACACA | |
| SCHEMBL29642175 | 0.86 | ACACB (0.47) | ACACBACACA | |
| SCHEMBL17580347 | 0.86 | ACACB (0.43) | ACACBACACA | |
| SCHEMBL17580298 | 0.86 | ACACB (0.43) | ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11912718-B2 | Solid forms of a thienopyrimidinedione ACC inhibitor and methods for production thereof | GILEAD APOLLO, LLC (US) | 2024-02-27 | — | — | US | disclosed |
| US-11912718-B2 | Solid forms of a thienopyrimidinedione ACC inhibitor and methods for production thereof | GILEAD APOLLO, LLC (US) | 2024-02-27 | — | — | US | disclosed |
| US-11673899-B2 | Crystal form of thieno[2,3-c]pyridazine-4(1H)-one compound, preparation method therefor and use thereof | ZHANGZHOU PIEN TZE HUANG PHARMACEUTICAL CO., LTD. (CN) | 2023-06-13 | — | — | US | disclosed |
| US-11673899-B2 | Crystal form of thieno[2,3-c]pyridazine-4(1H)-one compound, preparation method therefor and use thereof | ZHANGZHOU PIEN TZE HUANG PHARMACEUTICAL CO., LTD. (CN) | 2023-06-13 | — | — | US | disclosed |
| EP-3660023-B1 | THIENOPYRIMIDINEDIONE COMPOUNDS AS ACC INHIBITORS AND USE THEREOF | NANJING SANHOME PHARMACEUTICAL CO LTD (CN) | 2023-03-08 | — | — | EP | disclosed |
| EP-3660023-B1 | THIENOPYRIMIDINEDIONE COMPOUNDS AS ACC INHIBITORS AND USE THEREOF | NANJING SANHOME PHARMACEUTICAL CO LTD (CN) | 2023-03-08 | — | — | EP | disclosed |
| US-11186587-B2 | Compound as ACC inhibitor and use thereof | NANJING SANHOME PHARMACEUTICAL CO., LTD. (CN) | 2021-11-30 | — | — | US | disclosed |
| US-11186587-B2 | Compound as ACC inhibitor and use thereof | NANJING SANHOME PHARMACEUTICAL CO., LTD. (CN) | 2021-11-30 | — | — | US | disclosed |
| EP-3380478-B1 | ESTER ACC INHIBITORS AND USES THEREOF | GILEAD APOLLO LLC (US) | 2020-12-23 | — | — | EP | disclosed |
| EP-3660023-A1 | COMPOUND AS ACC INHIBITOR AND USE THEREOF | Nanjing Sanhome Pharmaceutical Co., Ltd. (CN) | 2020-06-03 | — | — | EP | disclosed |
| US-20200148699-A1 | SOLID FORMS OF A THIENOPYRIMIDINEDIONE ACC INHIBITOR AND METHODS FOR PRODUCTION THEREOF | GILEAD APOLLO, LLC | 2020-05-14 | — | — | US | disclosed |
| WO-2020015343-A1 | NOVEL COMPOUNDS AND THEIR USES AS ACC INHIBITORS | NANJING RUIJIE PHARMATECH CO., LTD. (CN) | 2020-01-23 | — | — | WO | disclosed |
| US-20190225623-A1 | SOLID FORMS OF A THIENOPYRIMIDINEDIONE ACC INHIBITOR AND METHODS FOR PRODUCTION THEREOF | NIMBUS DISCOVERY, INC. | 2019-07-25 | — | — | US | disclosed |
| WO-2019020041-A1 | COMPOUND AS ACC INHIBITOR AND USE THEREOF | 南京圣和药业股份有限公司 | 2019-01-31 | — | — | WO | disclosed |
| US-10183951-B2 | Solid forms of a thienopyrimidinedione ACC inhibitor and methods for production thereof | GILEAD APOLLO, LLC (US) | 2019-01-22 | — | — | US | disclosed |
| US-20170267690-A1 | SOLID FORMS OF A THIENOPYRIMIDINEDIONE ACC INHIBITOR AND METHODS FOR PRODUCTION THEREOF | J.P. LAWSON CONSULTING LLC | 2017-09-21 | — | — | US | disclosed |
| US-20170267690-A1 | SOLID FORMS OF A THIENOPYRIMIDINEDIONE ACC INHIBITOR AND METHODS FOR PRODUCTION THEREOF | J.P. LAWSON CONSULTING LLC | 2017-09-21 | — | — | US | disclosed |
| US-20170166583-A1 | ESTER ACC INHIBITORS AND USES THEREOF | Nimbus Apollo, Inc. | 2017-06-15 | — | — | US | disclosed |
| US-20170166583-A1 | ESTER ACC INHIBITORS AND USES THEREOF | Nimbus Apollo, Inc. | 2017-06-15 | — | — | US | disclosed |
| WO-2017091602-A1 | ESTER ACC INHIBITORS AND USES THEREOF | GILEAD APOLLO, LLC (US) | 2017-06-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170267690-A1 | SOLID FORMS OF A THIENOPYRIMIDINEDIONE ACC INHIBITOR AND METHODS FOR PRODUCTION THEREOF | ACACA, ACACB, COASY | ACACB 2/4885ACACA 1/4885 |
| US-20170166583-A1 | ESTER ACC INHIBITORS AND USES THEREOF | ACACA, ACACB, ACAT2 | ACACB 2/4885ACACA 1/4885 |
| US-11912718-B2 | Solid forms of a thienopyrimidinedione ACC inhibitor and methods for production thereof | ACACA, ACACB, COASY | ACACB 2/4885ACACA 1/4885 |
| US-20200148699-A1 | SOLID FORMS OF A THIENOPYRIMIDINEDIONE ACC INHIBITOR AND METHODS FOR PRODUCTION THEREOF | ACACA, ACACB, COASY | ACACB 2/4885ACACA 1/4885 |
| US-10183951-B2 | Solid forms of a thienopyrimidinedione ACC inhibitor and methods for production thereof | ACACA, ACACB, COASY | ACACB 2/4885ACACA 1/4885 |
| US-11673899-B2 | Crystal form of thieno[2,3-c]pyridazine-4(1H)-one compound, preparation method therefor and use thereof | WEE2, FAR1, WEE1 | ACACB 9/4885ACACA 11/4885 |
| US-20190225623-A1 | SOLID FORMS OF A THIENOPYRIMIDINEDIONE ACC INHIBITOR AND METHODS FOR PRODUCTION THEREOF | ACACA, ACACB, COASY | ACACB 2/4885ACACA 1/4885 |
| US-11186587-B2 | Compound as ACC inhibitor and use thereof | ACACA, ACACB, ACAT2 | ACACB 2/4885ACACA 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.