Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 3/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1891198 | 0.92 | ANO1 (0.61) | ANO1TP53THRBGRIN2CMEN1 | |
| SCHEMBL1952255 | 0.79 | GRIN2C (0.61) | ANO1GRIN2CMEN1KMT2ANPC1 | |
| SCHEMBL1954104 | 0.77 | ANO1 (0.74) | ANO1GRIN2CMEN1KMT2ANPC1 | |
| SCHEMBL1954521 | 0.73 | ANO1 (0.64) | ANO1 | |
| SCHEMBL1907496 | 0.72 | ANO1 (0.83) | ANO1GRIN2CMEN1KMT2ANPC1 | |
| SCHEMBL7950809 | 0.71 | ANO1 (0.70) | ANO1TP53THRBGRIN2CMEN1 | |
| SCHEMBL1953707 | 0.71 | GRIN2C (0.59) | ANO1GRIN2CMEN1KMT2ANPC1 | |
| SCHEMBL1953247 | 0.69 | ANO1 (1.00) | ANO1 | |
| SCHEMBL1894024 | 0.66 | ANO1 (0.54) | ANO1TP53THRBMEN1KMT2A | |
| SCHEMBL15479092 | 0.66 | F10 (0.55) | GRIN2CMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321303-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | Calcimedica, Inc. (US) | 2011-05-18 | — | — | EP | disclosed |
| WO-2010027875-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2010-03-11 | — | — | WO | disclosed |