SCHEMBL18912271

SCHEMBL18912271

CC(CNC(=O)c1cnc[nH]1)CC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 3/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.46
HRH4 Q9H3N8 3/20 0.43
HRH3 Q9Y5N1 3/20 0.43
KMT2A Q03164 2/20 0.40
QPCT Q16769 1/20 0.39
QPCTL Q9NXS2 1/20 0.39
ACACB O00763 1/20 0.39
ACR P10323 1/20 0.39
ALDH1A1 P00352 2/20 0.38
CYP3A4 P08684 1/20 0.38
GABRA1 P14867 1/20 0.38
TSHR P16473 1/20 0.38
NFKB1 P19838 1/20 0.38
GABRR1 P24046 1/20 0.38
GABRR2 P28476 1/20 0.38
GABRA5 P31644 1/20 0.38
GABRB2 P47870 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18912263 0.85 TP53 (0.44) TP53SMN1; SMN2NPC1RAB9AHRH4
SCHEMBL18912367 0.82 TP53 (0.48) TP53SMN1; SMN2NPC1RAB9AHRH4
SCHEMBL18912207 0.82 ACR (0.48) TP53SMN1; SMN2NPC1RAB9AHRH4
SCHEMBL12676574 0.75 TP53 (0.51) TP53SMN1; SMN2NPC1RAB9AHRH4
SCHEMBL16950289 0.72 TP53 (0.49) TP53SMN1; SMN2NPC1RAB9AHRH4
SCHEMBL18912264 0.72 ALDH1A1 (0.51) TP53SMN1; SMN2NPC1RAB9AKMT2A
SCHEMBL22901899 0.72 SMN1; SMN2 (0.53) TP53SMN1; SMN2NPC1RAB9AHRH3
SCHEMBL18912366 0.71 ACACB (0.52) TP53SMN1; SMN2NPC1RAB9AHRH4
SCHEMBL18912365 0.71 CYP1A2 (0.52) TP53SMN1; SMN2NPC1RAB9AKMT2A
SCHEMBL7522000 0.70 NPC1 (0.50) TP53SMN1; SMN2NPC1RAB9AHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170152443-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHI MEI CORPORATION (TW) 2017-06-01 US disclosed