SCHEMBL18912367

SCHEMBL18912367

CC(CNC(=O)c1cnc[nH]1)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 3/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
NPC1 O15118 3/20 0.48
RAB9A P51151 3/20 0.48
KMT2A Q03164 2/20 0.42
ACACB O00763 1/20 0.40
CPB2 Q96IY4 2/20 0.39
CPB1 P15086 1/20 0.39
CYP3A4 P08684 2/20 0.39
SLC7A5 Q01650 1/20 0.39
CPA1 P15085 1/20 0.38
QPCT Q16769 1/20 0.38
QPCTL Q9NXS2 1/20 0.38
ACR P10323 1/20 0.37
ITGB2 P05107 1/20 0.37
ICAM1 P05362 1/20 0.37
ITGAL P20701 1/20 0.37
ALDH1A1 P00352 1/20 0.37
GABRA1 P14867 1/20 0.37
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18912263 0.85 TP53 (0.44) TP53SMN1; SMN2NPC1RAB9AKMT2A
SCHEMBL18912207 0.84 ACR (0.48) TP53SMN1; SMN2NPC1RAB9AKMT2A
SCHEMBL18912271 0.82 TP53 (0.46) TP53SMN1; SMN2NPC1RAB9AKMT2A
SCHEMBL12676574 0.77 TP53 (0.51) TP53SMN1; SMN2NPC1RAB9AKMT2A
SCHEMBL16950289 0.74 TP53 (0.49) TP53SMN1; SMN2NPC1RAB9AKMT2A
SCHEMBL3530778 0.74 KDM4E (0.52)
SCHEMBL22901899 0.74 SMN1; SMN2 (0.53) TP53SMN1; SMN2NPC1RAB9AKMT2A
SCHEMBL7522000 0.72 NPC1 (0.50) TP53SMN1; SMN2NPC1RAB9AKMT2A
SCHEMBL22372181 0.72 SMN1; SMN2 (0.51) TP53SMN1; SMN2NPC1RAB9AKMT2A
SCHEMBL18912209 0.72 CYP3A4 (0.41) TP53SMN1; SMN2NPC1RAB9ACPB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170152443-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHI MEI CORPORATION (TW) 2017-06-01 US disclosed