Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | QPCT | Q16769 | 1/20 | 0.43 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PYGL | P06737 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16950289 | 0.83 | TP53 (0.49) | SMN1; SMN2TP53NPC1RAB9AKMT2A | |
| SCHEMBL7522000 | 0.81 | NPC1 (0.50) | SMN1; SMN2TP53NPC1RAB9AKMT2A | |
| SCHEMBL12676574 | 0.80 | TP53 (0.51) | SMN1; SMN2TP53ALDH1A1NPC1RAB9A | |
| SCHEMBL18912208 | 0.79 | RAB9A (0.47) | SMN1; SMN2TP53ALDH1A1NPC1RAB9A | |
| SCHEMBL18912256 | 0.77 | KDM4E (0.47) | SMN1; SMN2TP53NPC1RAB9AKMT2A | |
| SCHEMBL18912264 | 0.76 | ALDH1A1 (0.51) | SMN1; SMN2TP53ALDH1A1NPC1RAB9A | |
| SCHEMBL18912365 | 0.75 | CYP1A2 (0.52) | SMN1; SMN2TP53ALDH1A1NPC1RAB9A | |
| SCHEMBL18912207 | 0.74 | ACR (0.48) | SMN1; SMN2TP53NPC1RAB9AKMT2A | |
| SCHEMBL18912257 | 0.74 | CYP1A2 (0.55) | SMN1; SMN2TP53ALDH1A1NPC1RAB9A | |
| SCHEMBL18912261 | 0.74 | CYP1A2 (0.55) | SMN1; SMN2TP53ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12264138-B2 | Process for the preparation of microbiocidal oxadiazole derivatives | SYNGENTA CROP PROTECTION AG (CH) | 2025-04-01 | — | — | US | disclosed |
| US-20220194907-A1 | PROCESS FOR THE PREPARATION OF MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2022-06-23 | — | — | US | disclosed |
| US-11358957-B2 | Microbiocidal oxadiazole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2022-06-14 | — | — | US | disclosed |
| US-20200277287-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12264138-B2 | Process for the preparation of microbiocidal oxadiazole derivatives | CYP51A1, MPO, NOX5 | SMN1; SMN2 3586/4885TP53 4335/4885ALDH1A1 258/4885 |
| US-20200277287-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | PRF1, NOX1, ARG2 | SMN1; SMN2 2990/4885TP53 2659/4885ALDH1A1 544/4885 |
| US-11358957-B2 | Microbiocidal oxadiazole derivatives | PRF1, NOX1, ARG2 | SMN1; SMN2 2990/4885TP53 2659/4885ALDH1A1 544/4885 |
| US-20220194907-A1 | PROCESS FOR THE PREPARATION OF MICROBIOCIDAL OXADIAZOLE DERIVATIVES | CYP51A1, MPO, NOX5 | SMN1; SMN2 3586/4885TP53 4335/4885ALDH1A1 258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.